Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 16/20 | 0.70 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | HTR1B | P28222 | 2/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19847923 | 0.92 | MGLL (0.66) | MGLLNR3C2HTR1DHTR1AHTR1B | |
| SCHEMBL19833871 | 0.91 | MGLL (0.79) | MGLLNR3C2HTR1DHTR1AHTR1B | |
| SCHEMBL19833803 | 0.87 | MGLL (0.79) | MGLLNR3C2HTR1DHTR1AHTR1B | |
| SCHEMBL19847847 | 0.87 | MGLL (0.62) | MGLLNR3C2 | |
| SCHEMBL19847843 | 0.87 | MGLL (0.84) | MGLLNR3C2HTR1DHTR1AHTR1B | |
| SCHEMBL19834150 | 0.85 | MGLL (0.78) | MGLLHTR1DHTR1AHTR1B | |
| SCHEMBL19833740 | 0.85 | MGLL (0.74) | MGLLHTR1DHTR1AHTR1B | |
| SCHEMBL19833979 | 0.84 | MGLL (0.66) | MGLLNR3C2 | |
| SCHEMBL22386182 | 0.83 | MGLL (0.56) | MGLLNR3C2HTR1DHTR1AHTR1B | |
| SCHEMBL19834081 | 0.82 | MGLL (1.00) | MGLLNR3C2HTR1DHTR1AHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3279191-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2020-09-02 | — | — | EP | disclosed |