Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.64 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | HTR1D | P28221 | 2/20 | 0.51 |
| ▸ | HTR1B | P28222 | 1/20 | 0.51 |
| ▸ | NR3C2 | P08235 | 5/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19833748 | 0.91 | MGLL (0.68) | MGLLHTR1AHTR1DHTR1BNR3C2 | |
| SCHEMBL19833814 | 0.89 | MGLL (0.62) | MGLLHTR1AHTR1DHTR1BNR3C2 | |
| SCHEMBL19834035 | 0.88 | MGLL (0.63) | MGLLHTR1AHTR1DHTR1BNR3C2 | |
| SCHEMBL19834108 | 0.88 | MGLL (0.63) | MGLLHTR1AHTR1DHTR1BNR3C2 | |
| SCHEMBL19833821 | 0.88 | MGLL (0.64) | MGLLHTR1AHTR1DHTR1BNR3C2 | |
| SCHEMBL19834021 | 0.86 | MGLL (0.72) | MGLLHTR1AHTR1DHTR1BNR3C2 | |
| SCHEMBL19833718 | 0.85 | MGLL (0.71) | MGLLHTR1AHTR1DHTR1BNR3C2 | |
| SCHEMBL19833973 | 0.85 | MGLL (0.65) | MGLLHTR1AHTR1DHTR1BNR3C2 | |
| SCHEMBL19847892 | 0.84 | MGLL (0.75) | MGLLHTR1AHTR1DHTR1BNR3C2 | |
| SCHEMBL19833706 | 0.83 | MGLL (0.73) | MGLLHTR1AHTR1DHTR1BNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3279191-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2020-09-02 | — | — | EP | disclosed |
| EP-3279191-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2018-02-07 | — | — | EP | disclosed |