SCHEMBL19848740

SCHEMBL19848740

Fc1ccc2nnn(-c3ccncc3)c2c1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.45
FLT3 P36888 1/20 0.40
NT5E P21589 4/20 0.38
PDE10A Q9Y233 2/20 0.37
KDM4E B2RXH2 1/20 0.37
NPC1 O15118 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
PIM1 P11309 2/20 0.37
CLK1 P49759 1/20 0.35
DYRK1A Q13627 1/20 0.35
CYP11B2 P19099 2/20 0.35
MAPK9 P45984 1/20 0.35
MAPK10 P53779 1/20 0.35
CYP11B1 P15538 1/20 0.35
KCNMA1 Q12791 1/20 0.35
PIK3CD O00329 1/20 0.34
ESR1 P03372 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19911611 0.87 ALDH1A1 (0.49) ALDH1A1FLT3KDM4ENPC1L3MBTL1
SCHEMBL19848735 0.85 NPC1 (0.53) ALDH1A1NT5EKDM4ENPC1L3MBTL1
SCHEMBL19848336 0.80 NPC1 (0.55) ALDH1A1NT5EKDM4ENPC1L3MBTL1
SCHEMBL19911495 0.80 ALDH1A1 (0.45) ALDH1A1FLT3NT5EKDM4ENPC1
SCHEMBL19848320 0.80 L3MBTL1 (0.46) ALDH1A1NT5EPDE10AKDM4ENPC1
SCHEMBL19848488 0.76 ALDH1A1 (0.42) ALDH1A1NT5EKDM4ENPC1L3MBTL1
SCHEMBL19911524 0.76 HDAC3 (0.45) ALDH1A1NT5EPDE10AL3MBTL1PIM1
SCHEMBL19848168 0.75 ALDH1A1 (0.64) ALDH1A1KDM4ENPC1L3MBTL1MAPK9
SCHEMBL19848435 0.75 ALDH1A1 (0.46) ALDH1A1KDM4ENPC1L3MBTL1MAPK9
SCHEMBL19911554 0.74 ALDH1A1 (0.46) ALDH1A1NPC1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10756394-B2 Nonaqueous electrolyte and nonaqueous secondary battery ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-08-25 US disclosed
US-20180062213-A1 Nonaqueous Electrolyte and Nonaqueous Secondary Battery ASAHI KASEI KABUSHIKI KAISHA (JP) 2018-03-01 US disclosed
US-20180062213-A1 Nonaqueous Electrolyte and Nonaqueous Secondary Battery ASAHI KASEI KABUSHIKI KAISHA (JP) 2018-03-01 US disclosed
EP-3279997-A1 NONAQUEOUS ELECTROLYTE AND NONAQUEOUS SECONDARY BATTERY Asahi Kasei Kabushiki Kaisha (JP) 2018-02-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10756394-B2 Nonaqueous electrolyte and nonaqueous secondary battery BPTF, BRD4, KCNN2 ALDH1A1 3497/4885FLT3 482/4885NT5E 2513/4885
US-20180062213-A1 Nonaqueous Electrolyte and Nonaqueous Secondary Battery BPTF, BRD4, KCNN2 ALDH1A1 3497/4885FLT3 482/4885NT5E 2513/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.