SCHEMBL19848828

SCHEMBL19848828

O=C1c2cccc(-n3c4ccccc4c4cccc(C(F)(F)F)c43)c2C(=O)N1c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA1A P0DMV8 1/20 0.48
PABPC1 P11940 1/20 0.48
USP2 O75604 3/20 0.42
KMT2A Q03164 3/20 0.42
MAPT P10636 2/20 0.42
HTT P42858 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
MEN1 O00255 2/20 0.42
LMNA P02545 1/20 0.42
TNNI3 P19429 1/20 0.42
TNNT2 P45379 1/20 0.42
TNNC1 P63316 1/20 0.42
ALDH1A1 P00352 6/20 0.41
KDM4E B2RXH2 3/20 0.41
KEAP1 Q14145 1/20 0.41
NFE2L2 Q16236 1/20 0.41
POLB P06746 3/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
APOBEC3A P31941 1/20 0.40
RECQL P46063 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23516091 0.94 HSPA1A (0.51) HSPA1APABPC1USP2KMT2AMAPT
SCHEMBL19842428 0.94 PDE6D (0.46) HSPA1APABPC1USP2KMT2AMAPT
SCHEMBL19842524 0.92 HSPA1A (0.40) HSPA1APABPC1USP2KMT2AMAPT
SCHEMBL19842380 0.89 NR1H2 (0.44) HSPA1APABPC1HTTALDH1A1POLB
SCHEMBL19842444 0.88 NR1H2 (0.36) HSPA1APABPC1HTTALDH1A1POLB
SCHEMBL19848838 0.88 HSPA1A (0.44) HSPA1APABPC1USP2KMT2AMAPT
SCHEMBL19842424 0.88 PDE6D (0.48) HSPA1APABPC1USP2KMT2AMAPT
SCHEMBL23892907 0.87 PDE6D (0.44) HSPA1APABPC1USP2KMT2AMAPT
SCHEMBL19842514 0.86 HSPA1A (0.42) HSPA1APABPC1USP2KMT2AMAPT
SCHEMBL19848878 0.86 GALR3 (0.43) HSPA1APABPC1USP2KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11276825-B2 Organic molecules for use in organic devices CYNORA GMBH (DE) 2022-03-15 US disclosed
US-20210184134-A1 ORGANIC MOLECULES FOR USE IN ORGANIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2021-06-17 US disclosed
EP-3279193-B1 COMPOUNDS COMPRISING A PHTHALIMIDE GROUP AND CARBAZOLE OR ITS ANALOGUES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-05-08 EP disclosed
WO-2018024723-A1 PHTHALIMIDE AND CARBAZOLE OR ANALOGS THEREOF CONTAINING COMPOUNDS FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-08 WO disclosed
EP-3279193-A1 COMPOUNDS COMPRISING PHTHALIMIDE AND CARBAZOLE OR ITS ANALOGUES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210184134-A1 ORGANIC MOLECULES FOR USE IN ORGANIC DEVICES CHRM1, C1S, DNMT3L HSPA1A 4232/4885PABPC1 4768/4885USP2 3112/4885
US-11276825-B2 Organic molecules for use in organic devices AOX1, OR10J3, L1CAM HSPA1A 2535/4885PABPC1 2862/4885USP2 4145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.