Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19852647 | 0.95 | CASP3 (0.47) | CASP3BRD4TDP2CREBBPTDP1 | |
| SCHEMBL19848949 | 0.93 | CASP3 (0.43) | CASP3BRD4TDP2TDP1GABRA1 | |
| SCHEMBL23515911 | 0.91 | CHEK1 (0.39) | CASP3BRD4FLT3LMNATP53 | |
| SCHEMBL23515906 | 0.91 | CHEK1 (0.39) | CASP3BRD4FLT3 | |
| SCHEMBL19848968 | 0.89 | CASP3 (0.37) | CASP3BRD4TDP2CREBBPFLT3 | |
| SCHEMBL23515897 | 0.88 | PGR (0.39) | CASP3BRD4FLT3LMNATP53 | |
| SCHEMBL19848947 | 0.88 | CASP3 (0.47) | CASP3BRD4TDP2CREBBPTDP1 | |
| SCHEMBL23516312 | 0.87 | BRD4 (0.38) | CASP3BRD4FLT3LMNATP53 | |
| SCHEMBL23515926 | 0.86 | CHEK1 (0.41) | CASP3BRD4TDP2FLT3LMNA | |
| SCHEMBL23515905 | 0.86 | CHEK1 (0.39) | CASP3BRD4MEN1USP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3279193-B1 | COMPOUNDS COMPRISING A PHTHALIMIDE GROUP AND CARBAZOLE OR ITS ANALOGUES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2019-05-08 | — | — | EP | disclosed |
| WO-2018024723-A1 | PHTHALIMIDE AND CARBAZOLE OR ANALOGS THEREOF CONTAINING COMPOUNDS FOR USE IN ORGANIC OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2018-02-08 | — | — | WO | disclosed |
| EP-3279193-A1 | COMPOUNDS COMPRISING PHTHALIMIDE AND CARBAZOLE OR ITS ANALOGUES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2018-02-07 | — | — | EP | disclosed |