SCHEMBL1985013

SCHEMBL1985013

Cc1cc(C)c([C@H](N)[C@@H](N)c2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 3/20 0.39
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 2/20 0.39
LMNA P02545 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
TSHR P16473 1/20 0.38
SLC6A2 P23975 2/20 0.36
SLC6A4 P31645 2/20 0.36
SLC6A3 Q01959 2/20 0.36
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
HSD17B10 Q99714 1/20 0.31
NUDT1 P36639 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
F2 P00734 1/20 0.31
PRSS1 P07477 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1984068 1.00 RAPGEF4 (0.39) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL3194506 1.00 RAPGEF4 (0.39) RAPGEF4ALDH1A1KDM4ELMNAGAA
Hydrochloric Acid SCHEMBL7203084 0.97 SLC6A2 (0.39) RAPGEF4ALDH1A1KDM4ELMNAGAA
Hydrochloric Acid SCHEMBL20603134 0.95 SLC6A2 (0.38) RAPGEF4ALDH1A1KDM4ELMNAGAA
Hydrochloric Acid SCHEMBL14119547 0.95 SLC6A2 (0.38) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL23122285 0.80 RAPGEF4 (0.38) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL6442607 0.80 RAPGEF4 (0.38) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL8285929 0.80 RAPGEF4 (0.38) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL10292272 0.78 SLC6A2 (0.42) RAPGEF4ALDH1A1KDM4ELMNAGAA
Hydrochloric Acid SCHEMBL4936154 0.78 SLC6A2 (0.38) RAPGEF4ALDH1A1KDM4ELMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009112839-A1 COMPOUNDS AMURA THERAPEUTICS LIMITED (GB) 2009-09-17 WO claimed
EP-4340056-A1 POSITIVE ELECTRODE MIXTURE, POSITIVE ELECTRODE AND SECONDARY BATTERY Daikin Industries, Ltd. (JP) 2024-03-20 EP disclosed
US-20240088381-A1 POSITIVE ELECTRODE MIXTURE, POSITIVE ELECTRODE AND SECONDARY BATTERY DAIKIN INDUSTRIES, LTD. (JP) 2024-03-14 US disclosed
EP-4336584-A1 POSITIVE ELECTRODE MIXTURE, POSITIVE ELECTRODE AND SECONDARY BATTERY Daikin Industries, Ltd. (JP) 2024-03-13 EP disclosed
US-20240079595-A1 POSITIVE ELECTRODE MIXTURE, POSITIVE ELECTRODE AND SECONDARY BATTERY DAIKIN INDUSTRIES, LTD. (JP) 2024-03-07 US disclosed
CN-117280489-A Positive electrode mixture, positive electrode, and secondary battery 大金工业株式会社 2023-12-22 CN disclosed
CN-117223123-A Positive electrode mixture, positive electrode, and secondary battery 大金工业株式会社 2023-12-12 CN disclosed
CN-117223122-A Positive electrode mixture, positive electrode, and secondary battery 大金工业株式会社 2023-12-12 CN disclosed
EP-2146986-B1 DIPHENYL-DIHYDRO-IMIDAZOPYRIDINONES HOFFMANN LA ROCHE (CH) 2011-06-29 EP disclosed
US-7625895-B2 Diphenyl-dihydro-imidazopyridinones Hoffmann-Le Roche Inc. (US) 2009-12-01 US disclosed
US-7625895-B2 Diphenyl-dihydro-imidazopyridinones Hoffmann-Le Roche Inc. (US) 2009-12-01 US disclosed
US-7625895-B2 Diphenyl-dihydro-imidazopyridinones Hoffmann-Le Roche Inc. (US) 2009-12-01 US disclosed
US-20080255119-A1 DIPHENYL-DIHYDRO-IMIDAZOPYRIDINONES DOMINIQUE ROMYR 2008-10-16 US disclosed
US-20080255119-A1 DIPHENYL-DIHYDRO-IMIDAZOPYRIDINONES DOMINIQUE ROMYR 2008-10-16 US disclosed
US-20080255119-A1 DIPHENYL-DIHYDRO-IMIDAZOPYRIDINONES DOMINIQUE ROMYR 2008-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240079595-A1 POSITIVE ELECTRODE MIXTURE, POSITIVE ELECTRODE AND SECONDARY BATTERY MLX, AFF2, PYM1 RAPGEF4 956/4885ALDH1A1 4114/4885KDM4E 3227/4885
US-20080255119-A1 DIPHENYL-DIHYDRO-IMIDAZOPYRIDINONES TP53, MDM2, TP53BP1 RAPGEF4 2165/4885ALDH1A1 3275/4885KDM4E 2843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.