Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19850428 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2ALMNAHPGDALOX15 | |
| SCHEMBL19871712 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2ALMNAHPGDALOX15 | |
| SCHEMBL12269320 | 0.94 | SMN1; SMN2 (0.47) | SMN1; SMN2KMT2ALMNAHPGDALOX15 | |
| SCHEMBL2206280 | 0.90 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2ALMNAHPGDALOX15 | |
| SCHEMBL29818808 | 0.90 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2ALMNAHPGDALOX15 | |
| SCHEMBL7488776 | 0.88 | SMN1; SMN2 (0.60) | SMN1; SMN2KMT2ALMNAHPGDALOX15 | |
| SCHEMBL29818935 | 0.87 | LMNA (0.46) | SMN1; SMN2KMT2ALMNAHPGDALOX15 | |
| SCHEMBL4568888 | 0.85 | KMT2A (0.47) | SMN1; SMN2KMT2ALMNAHPGDTSHR | |
| SCHEMBL2205652 | 0.84 | SGMS2 (0.46) | SMN1; SMN2KMT2ALMNAHPGDALOX15 | |
| SCHEMBL2204430 | 0.84 | KMT2A (0.45) | SMN1; SMN2KMT2ALMNAHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3030519-B1 | TRICYCLIC BENZOXABOROLE COMPOUNDS AND USES THEREOF | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2022-01-05 | — | — | EP | disclosed |
| EP-3256479-B1 | 4 -SUBSTITUTED BENZOXABOROLE COMPOUNDS AND USES THEREOF | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2020-07-29 | — | — | EP | disclosed |
| US-20180037595-A1 | BENZOXABOROLE COMPOUNDS AND USES THEREOF | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2018-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180037595-A1 | BENZOXABOROLE COMPOUNDS AND USES THEREOF | BRD3, BRPF3, BRD4 | SMN1; SMN2 3699/4885KMT2A 2312/4885LMNA 1553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.