Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.31 |
| ▸ | LMNA | P02545 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27292935 | 0.89 | NPC1 (0.36) | MAP3K14CRBNNPC1GLAALDH1A1 | |
| SCHEMBL18888511 | 0.86 | NPC1 (0.40) | MAP3K14CRBNNPC1GLALMNA | |
| SCHEMBL5617171 | 0.84 | NPC1 (0.39) | MAP3K14CRBNNPC1LMNAALDH1A1 | |
| SCHEMBL4455145 | 0.83 | ALDH1A1 (0.40) | MAP3K14CRBNNPC1LMNAALDH1A1 | |
| SCHEMBL19657857 | 0.83 | ALDH1A1 (0.40) | MAP3K14CRBNNPC1LMNAALDH1A1 | |
| SCHEMBL9569047 | 0.83 | ALDH1A1 (0.40) | MAP3K14CRBNNPC1LMNAALDH1A1 | |
| SCHEMBL18473550 | 0.83 | ALDH1A1 (0.40) | MAP3K14CRBNNPC1LMNAALDH1A1 | |
| SCHEMBL6077509 | 0.83 | ALDH1A1 (0.40) | MAP3K14CRBNNPC1LMNAALDH1A1 | |
| SCHEMBL755754 | 0.82 | MAP3K14 (0.39) | MAP3K14CRBNNPC1GLABRD4 | |
| SCHEMBL22394491 | 0.80 | MAP3K14 (0.38) | MAP3K14CRBNNPC1GLABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023178641-A1 | DNA TOXIC DIMER COMPOUND AND CONJUGATE THEREOF | 成都百利多特生物药业有限责任公司 | 2023-09-28 | — | — | WO | disclosed |
| US-20180036421-A1 | METHODS OF MAKING DLL3 ANTIBODY DRUG CONJUGATES | ABBVIE STEMCENTRX LLC (US) | 2018-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180036421-A1 | METHODS OF MAKING DLL3 ANTIBODY DRUG CONJUGATES | DLK1, MCL1, LANCL1 | MAP3K14 2989/4885CRBN 364/4885NPC1 1883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.