SCHEMBL755754

SCHEMBL755754

CCC(C)C1CC(=O)NC1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAP3K14 Q99558 1/20 0.39
CRBN Q96SW2 3/20 0.37
GLA P06280 1/20 0.36
NPC1 O15118 1/20 0.35
ACE P12821 1/20 0.33
BRD4 O60885 1/20 0.32
CREBBP Q92793 1/20 0.32
HSD17B10 Q99714 2/20 0.31
RAB9A P51151 1/20 0.31
KDM4E B2RXH2 1/20 0.31
CYP1A2 P05177 2/20 0.31
CYP2C19 P33261 2/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
TSHR P16473 1/20 0.31
CYP19A1 P11511 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.30
HCAR2 Q8TDS4 1/20 0.30
LMNA P02545 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrrolidine SCHEMBL9110026 0.90 CRBN (0.33) MAP3K14CRBNGLANPC1HSD17B10
SCHEMBL20031168 0.82 NPC1 (0.41) MAP3K14CRBNGLANPC1KDM4E
SCHEMBL19851229 0.82 MAP3K14 (0.40) MAP3K14CRBNGLANPC1BRD4
SCHEMBL31435687 0.81 CRBN (0.40) CRBN
SCHEMBL20021318 0.80 NPC1 (0.40) MAP3K14CRBNGLANPC1ACE
SCHEMBL6078384 0.79 ALDH1A1 (0.41) MAP3K14CRBNNPC1ACEKDM4E
SCHEMBL6079243 0.79 ALDH1A1 (0.41) MAP3K14CRBNNPC1ACEKDM4E
SCHEMBL22085274 0.79 ALDH1A1 (0.41) MAP3K14CRBNNPC1ACEKDM4E
SCHEMBL27727578 0.79 ALDH1A1 (0.41) MAP3K14CRBNNPC1ACEKDM4E
SCHEMBL6077962 0.79 ALDH1A1 (0.41) MAP3K14CRBNNPC1ACEKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2431502-B1 CYANIDE-FREE SILVER ELECTROPLATING SOLUTIONS ROHM & HAAS ELECT MAT (US) 2017-05-24 EP claimed
CN-102409373-B Cyanide-free silver electroplating solutions ROHM AND HAAS COMPANY ELECT MATERIALS 2015-05-20 CN claimed
CN-102409372-B Method of electroplating silver strike over nickel ROHM & HAAS ELECT MAT 2015-02-11 CN claimed
EP-2431501-B1 Method of electroplating silver strike over nickel ROHM & HAAS ELECT MAT (US) 2013-11-20 EP claimed
CN-102409372-A Method of electroplating silver strike over nickel ROHM & HAAS ELECT MAT 2012-04-11 CN claimed
US-20120067733-A1 METHOD OF ELECTROPLATING SILVER STRIKE OVER NICKEL ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2012-03-22 US claimed
EP-2431501-A1 Method of electroplating silver strike over nickel Rohm and Haas Electronic Materials LLC (US) 2012-03-21 EP claimed
EP-0527186-A4 UNIV ILLINOIS (US) 1995-01-18 EP claimed
EP-0527186-A1 PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS The Board of Trustees for the University of Illinois (US) 1993-02-17 EP claimed
WO-1991016820-A1 PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1991-11-14 WO claimed
US-20220008549-A1 NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE AND ANTIBODY-DRUG CONJUGATE THEREOF DAIICHI SANKYO COMPANY, LIMITED (JP) 2022-01-13 US disclosed
US-20210236410-A1 HAIR COSMETIC COMPRISING BLOCK COPOLYMER SHISEIDO COMPANY, LTD. (JP) 2021-08-05 US disclosed
US-20210214514-A1 POROUS BODY, AND METHOD FOR PRODUCING POROUS BODY EMAUS KYOTO, INC. (JP) 2021-07-15 US disclosed
CN-112203635-A Inorganic particle dispersion liquid for cosmetic containing block copolymer 株式会社资生堂 2021-01-08 CN disclosed
CN-112203636-A Hair cosmetic comprising block copolymer 株式会社资生堂 2021-01-08 CN disclosed
CN-1741993-A Process for producing cyclic amines NEW JAPAN CHEM CO LTD (JP) 2006-03-01 CN disclosed
US-6210816-B1 Translucent xerographic recording substrates XEROX CORPORATION 2001-04-03 US disclosed
US-5622137-A FOR USE IN TESTING COOKED FOODS TRANS WORLD SERVICES (US) 1997-04-22 US disclosed
US-5242892-A With 5-aminolevulinic acid THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1993-09-07 US disclosed
US-4246077-A SILVER COMPLEX OF 3-PYRROLINE-2,5-DIONE OR PYRROLIDINE-2,5-DIONE TECHNIC, INC. (US) 1981-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220008549-A1 NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE AND ANTIBODY-DRUG CONJUGATE THEREOF STING1, CGAS, TLR9 MAP3K14 1509/4885CRBN 914/4885GLA 3244/4885
US-20210236410-A1 HAIR COSMETIC COMPRISING BLOCK COPOLYMER DNMT1, H1-0, H1-5 MAP3K14 4637/4885CRBN 2937/4885GLA 1312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.