Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.67 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | PLK4 | O00444 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1984376 | 0.99 | HDAC6 (0.64) | HDAC6HDAC4HDAC3HDAC1CNR1 | |
| SCHEMBL1984985 | 0.93 | HDAC3 (0.56) | HDAC6HDAC4HDAC3HDAC1CNR1 | |
| SCHEMBL2201363 | 0.80 | HDAC6 (1.00) | HDAC6HDAC4HDAC3HDAC1CNR1 | |
| SCHEMBL11776529 | 0.78 | HDAC6 (0.61) | HDAC6HDAC4HDAC3HDAC1CNR1 | |
| SCHEMBL11538808 | 0.75 | HDAC6 (0.54) | HDAC6HDAC4HDAC3HDAC1CNR1 | |
| SCHEMBL1985456 | 0.75 | JAK2 (0.46) | HDAC6HDAC4HDAC3KDM4EALDH1A1 | |
| SCHEMBL6907136 | 0.74 | MAPK11 (0.49) | KDM4ENPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL4219879 | 0.74 | HDAC1 (0.50) | HDAC6HDAC4HDAC3HDAC1KDM4E | |
| SCHEMBL12800947 | 0.73 | HDAC4 (0.45) | HDAC6HDAC4HDAC1ALDH1A1HPGD | |
| SCHEMBL1983871 | 0.73 | SMYD3 (0.46) | HDAC6HDAC4HDAC3ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222655-B1 | N-CYCL0ALKYLMETHYL-2-AMIN0THIAZ0LE-5-CARB0XAMIDES FOR USE IN PLANT DISEASE CONTROL | SUMITOMO CHEMICAL CO (JP) | 2011-06-29 | — | — | EP | disclosed |
| US-20100298391-A1 | AMIDE COMPOUNDS AND USE THEREOF FOR PLANT DISEASE CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-25 | — | — | US | disclosed |
| US-20100298391-A1 | AMIDE COMPOUNDS AND USE THEREOF FOR PLANT DISEASE CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-25 | — | — | US | disclosed |
| US-20100298391-A1 | AMIDE COMPOUNDS AND USE THEREOF FOR PLANT DISEASE CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-25 | — | — | US | disclosed |
| EP-2222655-A1 | N-CYCL0ALKYLMETHYL-2-AMIN0THIAZ0LE-5-CARB0XAMIDES FOR USE IN PLANT DISEASE CONTROL | Sumitomo Chemical Company, Limited (JP) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009066790-A1 | N-CYCL0ALKYLMETHYL-2-AMIN0THIAZ0LE-5-CARB0XAMIDES FOR USE IN PLANT DISEASE CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298391-A1 | AMIDE COMPOUNDS AND USE THEREOF FOR PLANT DISEASE CONTROL | CYC1, NAT1, CYCS | HDAC6 852/4885HDAC4 1051/4885HDAC3 340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.