Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1983871 | 0.99 | SMYD3 (0.46) | JAK2JAK1JAK3CA12CA1 | |
| SCHEMBL1986003 | 0.96 | SMYD3 (0.46) | JAK2JAK1JAK3CA12CA1 | |
| SCHEMBL12455912 | 0.81 | TP53 (0.44) | MAPK1HDAC3HDAC4HDAC6ACACB | |
| SCHEMBL11751760 | 0.77 | SMYD3 (0.43) | JAK2JAK1JAK3CA12CA1 | |
| SCHEMBL1987487 | 0.77 | LCK (0.39) | JAK2JAK1JAK3CA12CA1 | |
| SCHEMBL6907136 | 0.75 | MAPK11 (0.49) | SMYD3KDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL1985128 | 0.75 | HDAC6 (0.67) | CA2MAPK1HDAC3HDAC4HDAC6 | |
| SCHEMBL12599534 | 0.75 | ALDH1A1 (0.52) | JAK2JAK1JAK3CA12CA1 | |
| SCHEMBL1984376 | 0.73 | HDAC6 (0.64) | CA2MAPK1HDAC3HDAC4HDAC6 | |
| SCHEMBL1987380 | 0.73 | ALDH1A1 (0.54) | JAK2JAK1JAK3CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222655-B1 | N-CYCL0ALKYLMETHYL-2-AMIN0THIAZ0LE-5-CARB0XAMIDES FOR USE IN PLANT DISEASE CONTROL | SUMITOMO CHEMICAL CO (JP) | 2011-06-29 | — | — | EP | disclosed |
| EP-2222655-B1 | N-CYCL0ALKYLMETHYL-2-AMIN0THIAZ0LE-5-CARB0XAMIDES FOR USE IN PLANT DISEASE CONTROL | SUMITOMO CHEMICAL CO (JP) | 2011-06-29 | — | — | EP | disclosed |
| US-20100298391-A1 | AMIDE COMPOUNDS AND USE THEREOF FOR PLANT DISEASE CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-25 | — | — | US | disclosed |
| US-20100298391-A1 | AMIDE COMPOUNDS AND USE THEREOF FOR PLANT DISEASE CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-25 | — | — | US | disclosed |
| US-20100298391-A1 | AMIDE COMPOUNDS AND USE THEREOF FOR PLANT DISEASE CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-25 | — | — | US | disclosed |
| WO-2009066790-A1 | N-CYCL0ALKYLMETHYL-2-AMIN0THIAZ0LE-5-CARB0XAMIDES FOR USE IN PLANT DISEASE CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298391-A1 | AMIDE COMPOUNDS AND USE THEREOF FOR PLANT DISEASE CONTROL | CYC1, NAT1, CYCS | JAK2 2625/4885JAK1 1918/4885JAK3 3096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.