SCHEMBL1985141

SCHEMBL1985141

CC(C)COC(=O)C(C#N)=CC(=O)CO

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.44
MAPT P10636 5/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
TP53 P04637 1/20 0.41
TSHR P16473 3/20 0.41
KDM4E B2RXH2 3/20 0.40
THRB P10828 1/20 0.40
CYP2C9 P11712 1/20 0.38
LMNA P02545 1/20 0.34
POLB P06746 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PTP4A1 Q93096 1/20 0.31
MIF P14174 1/20 0.31
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
USP2 O75604 1/20 0.31
GAA P10253 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7743875 0.83 ALDH1A1 (0.50) ALDH1A1MAPTMEN1KMT2ATP53
SCHEMBL7547845 0.83 ALDH1A1 (0.50) ALDH1A1MAPTMEN1KMT2ATP53
SCHEMBL540781 0.81 CYP2C9 (0.57) ALDH1A1MAPTMEN1KMT2ATP53
SCHEMBL540323 0.80 ALDH1A1 (0.43) ALDH1A1MAPTMEN1KMT2ATP53
SCHEMBL2230964 0.79 CYP2C9 (0.42) ALDH1A1MAPTMEN1KMT2ATP53
SCHEMBL7549249 0.78 ALDH1A1 (0.47) ALDH1A1MAPTMEN1KMT2ATP53
SCHEMBL7549245 0.78 ALDH1A1 (0.47) ALDH1A1MAPTMEN1KMT2ATP53
SCHEMBL28040004 0.78 ALDH1A1 (0.47) ALDH1A1MAPTMEN1KMT2ATP53
SCHEMBL7548113 0.77 ALDH1A1 (0.46) ALDH1A1MAPTMEN1KMT2ATP53
SCHEMBL7547841 0.77 ALDH1A1 (0.46) ALDH1A1MAPTMEN1KMT2ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2515954-A1 OXIDIZED REGENERATED CELLULOSE ADHESIVE TAPE Advanced Technologies and Regenerative Medicine, LLC (US) 2012-10-31 EP claimed
WO-2011087722-A1 OXIDIZED REGENERATED CELLULOSE ADHESIVE TAPE ADVANCED TECHNOLOGIES AND REGENERATIVE MEDICINE, LLC (US) 2011-07-21 WO claimed
US-20110152924-A1 OXIDIZED REGENERATED CELLULOSE ADHESIVE TAPE ADVANCED TECHNOLOGIES AND REGENERATIVE MEDICINE, LLC 2011-06-23 US claimed
US-20110152924-A1 OXIDIZED REGENERATED CELLULOSE ADHESIVE TAPE ADVANCED TECHNOLOGIES AND REGENERATIVE MEDICINE, LLC 2011-06-23 US disclosed