Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 16/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19851668 | 0.94 | TLR2 (0.61) | TLR2 | |
| SCHEMBL19851636 | 0.90 | TLR2 (0.53) | TLR2 | |
| SCHEMBL19851727 | 0.87 | TLR2 (0.55) | TLR2EPHX2FAAH | |
| SCHEMBL19851681 | 0.78 | TLR2 (0.65) | TLR2 | |
| SCHEMBL19839562 | 0.78 | TLR2 (0.57) | TLR2 | |
| SCHEMBL19839849 | 0.78 | TLR2 (0.57) | TLR2 | |
| SCHEMBL19851737 | 0.77 | TLR2 (0.56) | TLR2EPHX2FAAH | |
| SCHEMBL19851489 | 0.77 | TSHR (0.55) | TLR2EPHX2FAAH | |
| SCHEMBL19851638 | 0.76 | TLR2 (0.90) | TLR2 | |
| SCHEMBL19839625 | 0.76 | TLR2 (0.57) | TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026866-A1 | LIPID-SUBSTITUTED AMINO 1,2-AND 1,3-DIOL COMPOUNDS AS MODULATORS OF TLR2 DIMERIZATION | NEUROPORE THERAPIES, INC. (US) | 2018-02-08 | — | — | WO | disclosed |