Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 3/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19851489 | 0.95 | TSHR (0.55) | TLR2EPHX2KDM4ELMNAFAAH | |
| SCHEMBL19851687 | 0.87 | HPGD (0.62) | TLR2EPHX2FAAHHPGDCNR2 | |
| SCHEMBL19851486 | 0.87 | HPGD (0.62) | TLR2EPHX2FAAHHPGDCNR2 | |
| SCHEMBL19851487 | 0.83 | SMN1; SMN2 (0.59) | KDM4ELMNATSHRRECQLHPGD | |
| SCHEMBL19851668 | 0.82 | TLR2 (0.61) | TLR2 | |
| SCHEMBL10380701 | 0.81 | ALDH1A1 (0.50) | EPHX2KDM4EFAAHRECQLHPGD | |
| SCHEMBL21657637 | 0.80 | KDM4E (0.59) | TLR2KDM4ELMNAHPGDCNR2 | |
| SCHEMBL8468019 | 0.79 | EPHX2 (0.74) | EPHX2LMNAFAAHTSHRRECQL | |
| SCHEMBL2368921 | 0.78 | EPHX2 (0.50) | TLR2EPHX2KDM4ELMNAFAAH | |
| SCHEMBL14112016 | 0.78 | EPHX2 (0.67) | TLR2EPHX2LMNAFAAHTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026866-A1 | LIPID-SUBSTITUTED AMINO 1,2-AND 1,3-DIOL COMPOUNDS AS MODULATORS OF TLR2 DIMERIZATION | NEUROPORE THERAPIES, INC. (US) | 2018-02-08 | — | — | WO | disclosed |