Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TLR2 | O60603 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19851737 | 0.95 | TLR2 (0.56) | TSHRRECQLEPHX2NPSR1HPGD | |
| SCHEMBL19851486 | 0.90 | HPGD (0.62) | EPHX2HPGDTLR2FAAHALDH1A1 | |
| SCHEMBL19851687 | 0.90 | HPGD (0.62) | EPHX2HPGDTLR2FAAHALDH1A1 | |
| SCHEMBL19851487 | 0.88 | SMN1; SMN2 (0.59) | TSHRRECQLHPGDALDH1A1KDM4E | |
| SCHEMBL19851668 | 0.82 | TLR2 (0.61) | TLR2 | |
| SCHEMBL10380701 | 0.81 | ALDH1A1 (0.50) | RECQLEPHX2HPGDFAAHALDH1A1 | |
| SCHEMBL13864789 | 0.80 | CASP2 (0.47) | TSHRRECQLEPHX2FAAHALDH1A1 | |
| SCHEMBL8468019 | 0.79 | EPHX2 (0.74) | TSHRRECQLEPHX2HPGDFAAH | |
| SCHEMBL13868783 | 0.78 | MEN1 (0.58) | TSHRRECQLNPSR1HPGDALDH1A1 | |
| SCHEMBL13864837 | 0.78 | TSHR (0.53) | TSHRRECQLEPHX2NPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026866-A1 | LIPID-SUBSTITUTED AMINO 1,2-AND 1,3-DIOL COMPOUNDS AS MODULATORS OF TLR2 DIMERIZATION | NEUROPORE THERAPIES, INC. (US) | 2018-02-08 | — | — | WO | disclosed |