Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 16/20 | 0.86 |
| ▸ | SIRT1 | Q96EB6 | 11/20 | 0.86 |
| ▸ | SIRT3 | Q9NTG7 | 11/20 | 0.86 |
| ▸ | TLR2 | O60603 | 3/20 | 0.71 |
| ▸ | CPB1 | P15086 | 1/20 | 0.67 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28291230 | 1.00 | SIRT2 (0.86) | SIRT2SIRT1SIRT3TLR2CPB1 | |
| SCHEMBL19851672 | 0.94 | SIRT2 (0.77) | SIRT2SIRT1SIRT3TLR2CPB1 | |
| SCHEMBL11737428 | 0.92 | CTSL (0.76) | SIRT2SIRT1SIRT3 | |
| SCHEMBL20542671 | 0.89 | SIRT2 (0.69) | SIRT2SIRT1SIRT3 | |
| SCHEMBL20542673 | 0.89 | SIRT2 (0.69) | SIRT2SIRT1SIRT3 | |
| SCHEMBL20542972 | 0.89 | SIRT2 (0.69) | SIRT2SIRT1SIRT3 | |
| SCHEMBL20545282 | 0.89 | SIRT2 (0.69) | SIRT2SIRT1SIRT3 | |
| SCHEMBL30891387 | 0.89 | SIRT2 (0.75) | SIRT2SIRT1SIRT3TLR2CPB1 | |
| SCHEMBL7388911 | 0.88 | SIRT2 (0.68) | SIRT2SIRT1SIRT3TLR2CPB1 | |
| SCHEMBL7324738 | 0.87 | SIRT2 (0.67) | SIRT2SIRT1SIRT3TLR2CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026866-A1 | LIPID-SUBSTITUTED AMINO 1,2-AND 1,3-DIOL COMPOUNDS AS MODULATORS OF TLR2 DIMERIZATION | NEUROPORE THERAPIES, INC. (US) | 2018-02-08 | — | — | WO | disclosed |