Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.76 |
| ▸ | CTSS | P25774 | 1/20 | 0.76 |
| ▸ | SIRT2 | Q8IXJ6 | 18/20 | 0.74 |
| ▸ | SIRT1 | Q96EB6 | 14/20 | 0.74 |
| ▸ | SIRT3 | Q9NTG7 | 11/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766104 | 0.93 | CTSL (0.76) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL19851643 | 0.92 | SIRT2 (0.86) | SIRT2SIRT1SIRT3 | |
| SCHEMBL28291230 | 0.92 | SIRT2 (0.86) | SIRT2SIRT1SIRT3 | |
| SCHEMBL8767026 | 0.92 | CTSL (0.77) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL20542972 | 0.92 | SIRT2 (0.69) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL20542673 | 0.92 | SIRT2 (0.69) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL20545282 | 0.92 | SIRT2 (0.69) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL20542671 | 0.92 | SIRT2 (0.69) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL671485 | 0.91 | SIRT2 (0.65) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL16601896 | 0.91 | CTSL (0.67) | CTSLCTSSSIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4022606-A | Antimicrobial use of ω-aminocarboxylic acid amides | HENKEL & CIE G.M.B.H. (DT) | 1977-05-10 | — | — | US | disclosed |