Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 7/20 | 0.44 |
| ▸ | PLA2G2C | Q5R387 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19851654 | 0.87 | TLR2 (0.61) | TLR2 | |
| SCHEMBL19851856 | 0.87 | TLR2 (0.61) | TLR2 | |
| SCHEMBL19851651 | 0.79 | TLR2 (0.55) | TLR2PLA2G2CCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL24470524 | 0.77 | TLR2 (0.61) | TLR2 | |
| SCHEMBL30503013 | 0.77 | TLR2 (0.61) | TLR2 | |
| SCHEMBL19851719 | 0.76 | CTSK (0.51) | TLR2TDP1CA12CA1CA2 | |
| SCHEMBL24096052 | 0.76 | TDP1 (0.58) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL19851706 | 0.75 | TLR2 (0.65) | TLR2TDP1 | |
| SCHEMBL9017485 | 0.74 | TDP1 (0.56) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL24485595 | 0.73 | PLA2G2C (0.57) | PLA2G2CUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026866-A1 | LIPID-SUBSTITUTED AMINO 1,2-AND 1,3-DIOL COMPOUNDS AS MODULATORS OF TLR2 DIMERIZATION | NEUROPORE THERAPIES, INC. (US) | 2018-02-08 | — | — | WO | disclosed |