Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 17/20 | 0.41 |
| ▸ | MC4R | P32245 | 2/20 | 0.39 |
| ▸ | MC5R | P33032 | 2/20 | 0.39 |
| ▸ | MC3R | P41968 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19851536 | 0.80 | MC4R (0.49) | MC4RMC5RMC3RMAPK1 | |
| Hydrochloric Acid SCHEMBL19839637 | 0.71 | TLR2 (0.53) | CASRMC4RMC5RMC3R | |
| SCHEMBL19851627 | 0.69 | CASR (0.44) | CASRMEN1KMT2ACYP2D6SLC6A2 | |
| SCHEMBL14726523 | 0.60 | KDM4E (0.47) | MEN1HTTKMT2A | |
| SCHEMBL11387212 | 0.60 | KDM4E (0.50) | MEN1MAPTHTTKMT2A | |
| SCHEMBL11235646 | 0.60 | KDM4E (0.53) | HTTKMT2A | |
| SCHEMBL10971746 | 0.60 | MEN1 (0.66) | CASRMEN1GAAMAPTMAPK1 | |
| SCHEMBL11935007 | 0.59 | MC5R (0.88) | MC4RMC5RMC3RMAPK1 | |
| SCHEMBL9609729 | 0.59 | MC5R (0.41) | CASRMC4RMC5RMC3RMEN1 | |
| SCHEMBL30380055 | 0.59 | MC5R (1.00) | MC4RMC5RMC3RMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026866-A1 | LIPID-SUBSTITUTED AMINO 1,2-AND 1,3-DIOL COMPOUNDS AS MODULATORS OF TLR2 DIMERIZATION | NEUROPORE THERAPIES, INC. (US) | 2018-02-08 | — | — | WO | disclosed |