Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.77 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | BMP1 | P13497 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1986948 | 0.89 | GHSR (0.71) | GHSRPOLB | |
| SCHEMBL1990385 | 0.87 | GHSR (1.00) | GHSRALDH1A1POLBNPC1RAB9A | |
| SCHEMBL10121677 | 0.85 | GHSR (0.71) | GHSRNQO1GSK3AGSK3BPAX8 | |
| SCHEMBL10122110 | 0.85 | GHSR (0.71) | GHSRNQO1GSK3AGSK3BALDH1A1 | |
| SCHEMBL10121929 | 0.85 | GHSR (0.70) | GHSRNQO1GSK3AGSK3BALDH1A1 | |
| SCHEMBL1981207 | 0.82 | GHSR (0.81) | GHSRPOLB | |
| SCHEMBL1981210 | 0.82 | GHSR (0.81) | GHSRPOLB | |
| SCHEMBL1989790 | 0.82 | GHSR (0.72) | GHSR | |
| SCHEMBL1990788 | 0.82 | GHSR (0.78) | GHSRALDH1A1POLBBMP1ADRB2 | |
| SCHEMBL17631733 | 0.81 | GHSR (0.82) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152232-A1 | SULFONAMIDE COMPOUNDS AND USES THEREOF | SAUNDERS JEFFREY O | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152232-A1 | SULFONAMIDE COMPOUNDS AND USES THEREOF | GHSR, GHRHR, SSTR2 | GHSR 1/4885NQO1 2581/4885GSK3A 2376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.