SCHEMBL19851949

SCHEMBL19851949

C=CC(=O)Oc1ccc(C#Cc2ccc(N)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 6/20 0.50
THRB P10828 4/20 0.46
MAPT P10636 2/20 0.42
ACACB O00763 2/20 0.39
TDP1 Q9NUW8 2/20 0.38
KDM4E B2RXH2 1/20 0.38
GLA P06280 1/20 0.38
GAA P10253 1/20 0.38
BLM P54132 1/20 0.38
CASP6 P55212 1/20 0.38
GFER P55789 1/20 0.38
FFAR1 O14842 1/20 0.38
PARP10 Q53GL7 1/20 0.37
F2 P00734 2/20 0.36
PRSS1 P07477 2/20 0.36
PRSS2 P07478 2/20 0.36
PRSS3 P35030 2/20 0.36
PKM P14618 1/20 0.36
KMT2A Q03164 1/20 0.36
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16182694 0.91 THRB (0.53) APPTHRBACACBKDM4EFFAR1
SCHEMBL12348184 0.91 THRB (0.53) APPTHRBACACBKDM4EFFAR1
SCHEMBL3291664 0.89 THRB (0.55) THRBMAPTTDP1KDM4EGLA
SCHEMBL14558156 0.84 FFAR1 (0.54) APPTHRBMAPTACACBFFAR1
SCHEMBL26862337 0.84 THRB (0.51) APPTHRBACACBFFAR1
SCHEMBL13859709 0.84 THRB (0.50) THRBMAPTTDP1KDM4EGLA
SCHEMBL14980965 0.83 THRB (0.46) APPTHRBACACBFFAR1
SCHEMBL13297284 0.83 THRB (0.50) APPTHRBACACBGAAFFAR1
SCHEMBL816437 0.83 THRB (0.46) THRBMAPTACACBKDM4EPARP10
SCHEMBL17370463 0.80 THRB (0.44) APPTHRBACACBFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210108142-A1 POLARIZED LUMINESCENT FILM DIC CORPORATION (JP) 2021-04-15 US disclosed
US-20180037680-A1 LAYERED BODY AND OPTICAL FILM OR LIQUID CRYSTAL ALIGNMENT FILM USING SAME DIC CORPORATION (JP) 2018-02-08 US disclosed