SCHEMBL816437

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL343191	0.95	THRB (0.50)	THRBF2PARP15PARP10PARP2
	SCHEMBL12348184	0.91	THRB (0.53)	THRBKDM4EMEN1RAB9AKMT2A
	SCHEMBL16182694	0.91	THRB (0.53)	THRBKDM4EMEN1RAB9AKMT2A
	SCHEMBL103216	0.90	MMP2 (0.51)	THRBF2PARP15PARP10PARP2
	SCHEMBL18328879	0.85	PPARD (0.43)	THRBF2PARP15PARP10PARP2
	SCHEMBL12354572	0.85	ALDH1A1 (0.50)	THRBF2PARP15PARP10PARP2
	SCHEMBL14558156	0.84	FFAR1 (0.54)	THRBMAPTACACB
	SCHEMBL14275339	0.83	KMT2A (0.50)	THRBMAPTMEN1LMNAKMT2A
	SCHEMBL13297284	0.83	THRB (0.50)	THRBLMNAALDH1A1CA1CA2
	SCHEMBL19851949	0.83	APP (0.50)	THRBF2PARP10MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.