Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.63 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.63 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.63 |
| ▸ | PTPRC | P08575 | 4/20 | 0.55 |
| ▸ | PTPN13 | Q12923 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18302951 | 0.83 | HDAC3 (0.61) | HDAC8HDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL155039 | 0.83 | SMYD3 (0.53) | HDAC8HDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL18302934 | 0.80 | SMYD3 (0.68) | HDAC8HDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL28449768 | 0.80 | HDAC3 (0.57) | HDAC8HDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL29415336 | 0.80 | HDAC3 (0.57) | HDAC8HDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL19692129 | 0.80 | HDAC3 (0.58) | HDAC8HDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL153425 | 0.79 | SMYD3 (0.57) | HDAC8HDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL29642969 | 0.79 | SMYD3 (0.57) | HDAC8HDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL22006782 | 0.79 | SMYD3 (0.54) | HDAC8HDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL16409770 | 0.79 | HDAC3 (0.69) | HDAC8HDAC3HDAC4HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025726-A1 | Novel Hybrid Compounds | UNIVERSITY OF GREENWICH (GB) | 2012-03-01 | — | — | WO | disclosed |