Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19852064 | 0.82 | ALDH1A1 (0.32) | TDP1ALDH1A1 | |
| SCHEMBL16674848 | 0.78 | TDP1 (0.36) | TDP1ALDH1A1 | |
| SCHEMBL11124467 | 0.78 | — | — | |
| SCHEMBL28427748 | 0.76 | — | — | |
| SCHEMBL22586427 | 0.76 | — | — | |
| SCHEMBL13716242 | 0.76 | CES1 (0.38) | ALDH1A1 | |
| SCHEMBL4742487 | 0.74 | — | — | |
| SCHEMBL11372614 | 0.74 | — | — | |
| SCHEMBL2542743 | 0.73 | TDP1 (0.36) | TDP1ALDH1A1LMNAALOX15BLM | |
| SCHEMBL24794903 | 0.73 | TRPA1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026371-A1 | DUAL NAV1.2/5HT2A INHIBITORS FOR TREATING CNS DISORDERS | SUNOVION PHARMACEUTICALS INC. (US) | 2018-02-08 | — | — | WO | disclosed |