Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.62 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.61 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.61 |
| ▸ | CCR3 | P51677 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19852051 | 0.91 | CARM1 (0.64) | SIGMAR1CARM1PRMT6CCR3MEN1 | |
| SCHEMBL19852043 | 0.87 | SIGMAR1 (0.71) | SIGMAR1CARM1PRMT6HRH3 | |
| SCHEMBL5522026 | 0.85 | LMNA (0.61) | MEN1KMT2AKCNH2LMNAPOLB | |
| SCHEMBL30584824 | 0.83 | CARM1 (0.62) | SIGMAR1CARM1PRMT6CYP2D6 | |
| SCHEMBL5545161 | 0.83 | CARM1 (0.62) | SIGMAR1CARM1PRMT6HRH3HTR2A | |
| SCHEMBL5545936 | 0.82 | CARM1 (0.61) | SIGMAR1CARM1PRMT6HRH3HTR2A | |
| Hydrochloric Acid SCHEMBL31546342 | 0.82 | CARM1 (0.61) | SIGMAR1CARM1PRMT6 | |
| SCHEMBL15961314 | 0.82 | SIGMAR1 (0.64) | SIGMAR1HRH3 | |
| SCHEMBL5537846 | 0.81 | CARM1 (0.68) | CARM1PRMT6HRH3HTR2ALMNA | |
| SCHEMBL4855546 | 0.81 | HRH3 (0.74) | SIGMAR1CARM1PRMT6CCR3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026371-A1 | DUAL NAV1.2/5HT2A INHIBITORS FOR TREATING CNS DISORDERS | SUNOVION PHARMACEUTICALS INC. (US) | 2018-02-08 | — | — | WO | disclosed |