Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19851976 | 1.00 | DGAT1 (0.31) | DGAT1NOS1NOS3NOS2PRKCA | |
| SCHEMBL19852218 | 0.92 | — | — | |
| SCHEMBL19852091 | 0.92 | — | — | |
| SCHEMBL19851975 | 0.81 | CYP4F2 (0.36) | PRKCA | |
| SCHEMBL19852089 | 0.79 | SLC1A3 (0.34) | — | |
| SCHEMBL19851970 | 0.79 | SLC1A3 (0.34) | — | |
| SCHEMBL14701571 | 0.79 | SLC1A3 (0.34) | — | |
| SCHEMBL17722388 | 0.78 | DGAT1 (0.44) | DGAT1 | |
| SCHEMBL22348975 | 0.77 | — | — | |
| SCHEMBL12120664 | 0.74 | TSHR (0.39) | PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10640725-B2 | Thermocleavable friction modifiers and methods thereof | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2020-05-05 | — | — | US | disclosed |
| US-20180037840-A1 | THERMOCLEAVABLE FRICTION MODIFIERS AND METHODS THEREOF | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180037840-A1 | THERMOCLEAVABLE FRICTION MODIFIERS AND METHODS THEREOF | F12, F5, F3 | DGAT1 1401/4885NOS1 2384/4885NOS3 2340/4885 |
| US-10640725-B2 | Thermocleavable friction modifiers and methods thereof | F12, F5, F3 | DGAT1 1401/4885NOS1 2384/4885NOS3 2340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.