Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | CAD | P27708 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18924778 | 0.91 | MMP8 (0.35) | CYP4F2CYP4A11MMP8ALDH1A1 | |
| SCHEMBL14873510 | 0.84 | MMP8 (0.37) | CYP4F2CYP4A11MMP8ALDH1A1LMNA | |
| SCHEMBL19852090 | 0.81 | DGAT1 (0.31) | PRKCA | |
| SCHEMBL19851976 | 0.81 | DGAT1 (0.31) | PRKCA | |
| SCHEMBL18856237 | 0.81 | CA2 (0.36) | CYP4F2CYP4A11LMNAL3MBTL1CPB2 | |
| SCHEMBL20381855 | 0.81 | FAAH (0.36) | CYP4F2CYP4A11LMNAL3MBTL1CPB2 | |
| SCHEMBL14873553 | 0.80 | CYP4F2 (0.52) | CYP4F2CYP4A11MMP8ALDH1A1LMNA | |
| SCHEMBL19851970 | 0.79 | SLC1A3 (0.34) | — | |
| SCHEMBL19852089 | 0.79 | SLC1A3 (0.34) | — | |
| SCHEMBL14701571 | 0.79 | SLC1A3 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10640725-B2 | Thermocleavable friction modifiers and methods thereof | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2020-05-05 | — | — | US | disclosed |
| US-20180037840-A1 | THERMOCLEAVABLE FRICTION MODIFIERS AND METHODS THEREOF | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180037840-A1 | THERMOCLEAVABLE FRICTION MODIFIERS AND METHODS THEREOF | F12, F5, F3 | CYP4F2 4222/4885CYP4A11 2737/4885MMP8 684/4885 |
| US-10640725-B2 | Thermocleavable friction modifiers and methods thereof | F12, F5, F3 | CYP4F2 4222/4885CYP4A11 2737/4885MMP8 684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.