SCHEMBL198522

SCHEMBL198522

CC(=O)N(C)c1ccc(Cl)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FSCN1 Q16658 1/20 0.55
SMN1; SMN2 Q16637 6/20 0.52
ALDH1A1 P00352 5/20 0.50
POLB P06746 3/20 0.50
RAB9A P51151 3/20 0.50
NPC1 O15118 2/20 0.50
AHR P35869 1/20 0.50
MAPT P10636 2/20 0.49
TDP1 Q9NUW8 1/20 0.48
ACLY P53396 1/20 0.47
LMNA P02545 4/20 0.46
CHRNB2 P17787 1/20 0.46
CHRNB4 P30926 1/20 0.46
CHRNA3 P32297 1/20 0.46
CHRNA4 P43681 1/20 0.46
KDM4E B2RXH2 2/20 0.46
HTT P42858 2/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
GPBAR1 Q8TDU6 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14341655 0.88 SMN1; SMN2 (0.61) FSCN1SMN1; SMN2ALDH1A1POLBRAB9A
SCHEMBL12550518 0.84 POLB (0.50) FSCN1SMN1; SMN2ALDH1A1POLBRAB9A
SCHEMBL692996 0.82 ALDH1A1 (0.48) SMN1; SMN2ALDH1A1POLBRAB9ANPC1
SCHEMBL2095575 0.82 ALDH1A1 (0.48) FSCN1SMN1; SMN2ALDH1A1POLBRAB9A
SCHEMBL8986913 0.82 ALDH1A1 (0.48) FSCN1SMN1; SMN2ALDH1A1POLBRAB9A
SCHEMBL12527997 0.81 ALDH1A1 (0.56) SMN1; SMN2ALDH1A1POLBRAB9ANPC1
SCHEMBL2392362 0.80 ALDH1A1 (0.54) FSCN1SMN1; SMN2ALDH1A1POLBRAB9A
Hydrochloric Acid SCHEMBL11842627 0.80 ALDH1A1 (0.47) SMN1; SMN2ALDH1A1POLBRAB9ANPC1
SCHEMBL12435790 0.80 ALDH1A1 (0.47) FSCN1SMN1; SMN2ALDH1A1POLBRAB9A
SCHEMBL7828029 0.80 ALDH1A1 (0.47) FSCN1SMN1; SMN2ALDH1A1POLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005075471-A2 THIAZOL-COMPOUNDS AS 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS BIOVITRUM AB (SE) 2005-08-18 WO claimed
US-12351924-B2 Electroreductive cross coupling OHIO STATE INNOVATION FOUNDATION (US) 2025-07-08 US disclosed
US-20230250539-A1 ELECTROREDUCTIVE CROSS COUPLING OHIO STATE INNOVATION FOUNDATION 2023-08-10 US disclosed
CN-112851538-B Method for promoting acylation of amine or alcohol by carbon dioxide 中国科学院兰州化学物理研究所 2022-05-20 CN disclosed
US-20220098214-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATING FIBROSIS YALE UNIVERSITY 2022-03-31 US disclosed
CN-112851538-A Method for promoting acylation of amine or alcohol by carbon dioxide 中国科学院兰州化学物理研究所 2021-05-28 CN disclosed
WO-2019016385-A1 BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES BASF SE (DE) 2019-01-24 WO disclosed
WO-2017214505-A1 CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE BIOMARIN PHARMACEUTICAL INC. (US) 2017-12-14 WO disclosed
CN-103214329-B Preparation method of N-methylformamide catalyzed by metallic copper salt UNIV ZHEJIANG 2014-12-10 CN disclosed
CN-103214329-A Preparation method of N-methylformamide catalyzed by metallic copper salt UNIV ZHEJIANG 2013-07-24 CN disclosed
US-20110046336-A1 TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX SUMITOMO CHEMICAL COMPANY, LIMITED 2011-02-24 US disclosed
CN-101827854-A Transition metal complex and method for producing conjugated aromatic compound using same SUMITOMO CHEMICAL CO 2010-09-08 CN disclosed
US-20100184978-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-07-22 US disclosed
CN-101772508-A Bipyridine compound, transition metal complex, and method for production of conjugated aromatic compound using the transition metal complex SUMITOMO CHEMICAL CO 2010-07-07 CN disclosed
EP-2192124-A1 TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND WITH THE TRANSITION METAL COMPLEX Sumitomo Chemical Company, Limited (JP) 2010-06-02 EP disclosed
EP-2172470-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX Sumitomo Chemical Company, Limited (JP) 2010-04-07 EP disclosed
EP-0686636-B1 TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES MEIJI SEIKA CO (JP) 2001-04-04 EP disclosed
US-5840895-A INTERMEDIATES FOR ANTIALLERGENS MEIJI SEIKA KABUSHIKI KAISHA (JP) 1998-11-24 US disclosed
US-5686442-A ANTIALLERGENS MEIJI SEIKA KABUSHIKI KAISHA (JP) 1997-11-11 US disclosed
EP-0686636-A1 TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES MEIJI SEIKA KABUSHIKI KAISHA (JP) 1995-12-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110046336-A1 TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX C9, C5, AP1M1 FSCN1 4488/4885SMN1; SMN2 3838/4885ALDH1A1 974/4885
US-20100184978-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX C9, C5, AP2M1 FSCN1 4703/4885SMN1; SMN2 4123/4885ALDH1A1 1092/4885
US-20220098214-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATING FIBROSIS DUSP5, DUSP4, DUSP6 FSCN1 943/4885SMN1; SMN2 3092/4885ALDH1A1 1762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.