Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30937240 | 0.85 | ALDH1A1 (0.41) | ALDH1A1POLBTDP1CHRNB2CHRNB4 | |
| SCHEMBL12550518 | 0.84 | POLB (0.50) | ALDH1A1POLBTDP1CHRNB2CHRNB4 | |
| SCHEMBL692996 | 0.82 | ALDH1A1 (0.48) | ALDH1A1POLBTDP1CHRNB2CHRNB4 | |
| SCHEMBL198522 | 0.82 | FSCN1 (0.55) | ALDH1A1POLBTDP1CHRNB2CHRNB4 | |
| SCHEMBL11616779 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MAPTSMN1; SMN2GPBAR1TSHR | |
| SCHEMBL2095575 | 0.82 | ALDH1A1 (0.48) | ALDH1A1POLBTDP1CHRNB2CHRNB4 | |
| SCHEMBL11870667 | 0.81 | CES2 (0.44) | ALDH1A1POLBTDP1MAPTSMN1; SMN2 | |
| SCHEMBL7828029 | 0.80 | ALDH1A1 (0.47) | ALDH1A1POLBTDP1CHRNB2CHRNB4 | |
| SCHEMBL12435790 | 0.80 | ALDH1A1 (0.47) | ALDH1A1POLBTDP1CHRNB2CHRNB4 | |
| SCHEMBL10942532 | 0.80 | ALDH1A1 (0.47) | ALDH1A1POLBTDP1CHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4702033-A1 | DESMURAMYLPEPTIDE DIACIDS AS NOD2 AGONISTS AND USE THEREOF | Imhotex Limited (GB) | 2026-03-04 | — | — | EP | disclosed |
| EP-4608816-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | Monte Rosa Therapeutics AG (CH) | 2025-09-03 | — | — | EP | disclosed |
| US-20250263395-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | MONTE ROSA THERAPEUTICS AG (CH) | 2025-08-21 | — | — | US | disclosed |
| WO-2024224093-A1 | DESMURAMYLPEPTIDE DIEESTERS AS NOD2 AGONISTS AND USE THEREOF | Imhotex Limited (GB) | 2024-10-31 | — | — | WO | disclosed |
| WO-2024224086-A1 | DESMURAMYLPEPTIDE DIACIDS AS NOD2 AGONISTS AND USE THEREOF | Imhotex Limited (GB) | 2024-10-31 | — | — | WO | disclosed |
| WO-2024092039-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-05-02 | — | — | WO | disclosed |
| US-10583140-B2 | Ingenol analogs, pharmaceutical compositions and methods of use thereof | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-03-10 | — | — | US | disclosed |
| US-20190030029-A1 | INGENOL ANALOGS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-01-31 | — | — | US | disclosed |
| WO-2018109496-A2 | UNNATURAL AMINO ACIDS | THE UNIVERSITY OF BRISTOL (GB) | 2018-06-21 | — | — | WO | disclosed |
| EP-2655323-B1 | INGENOL-3-ACYLATES III AND INGENOL-3-CARBAMATES | LEO LABORATORIES LTD (IE) | 2017-12-20 | — | — | EP | disclosed |
| EP-2655323-A1 | INGENOL-3-ACYLATES III AND INGENOL-3-CARBAMATES | LEO LABORATORIES LIMITED (IE) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012083953-A1 | INGENOL-3-ACYLATES III AND INGENOL-3-CARBAMATES | LEO PHARMA A/S (DK) | 2012-06-28 | — | — | WO | disclosed |
| EP-0572782-B1 | 1-Aryl-3-(3,4-dihydro-4-oxo-3-quinazolinyl)-urea fungicidal agents | AMERICAN CYANAMID CO (US) | 1996-06-26 | — | — | EP | disclosed |
| US-5354755-A | Agricultural uses | AMERICAN CYANAMID COMPANY (US) | 1994-10-11 | — | — | US | disclosed |
| US-5276038-A | 1-aryl-3-(3,4-dihydro-4-oxo-3-quinazolinyl)urea fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1994-01-04 | — | — | US | disclosed |
| EP-0572782-A1 | 1-Aryl-3-(3,4-dihydro-4-oxo-3-quinazolinyl)-urea fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1993-12-08 | — | — | EP | disclosed |
| US-4053298-A | HERBICIDAL COMPOSITIONS CONTAINING 1-THIADIAZOLYL-6-CARBAMOYLOXYTETRAHYDROPYRIMIDINONES AND METHODS THEREFOR | VELSICOL CHEMICAL CORPORATION (US) | 1977-10-11 | — | — | US | disclosed |
| US-4023957-A | Herbicidal 1-thiadiazolyl-5-carbamoyloxyimidazolidinones | VELSICOL CHEMICAL CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |
| US-3989710-A | POSTEMERGENCE HERBICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-02 | — | — | US | disclosed |
| US-3951976-A | 1-Thiadiazoly-6-carbamoyloxytetrahydropyrimidinones | VELSICOL CHEMICAL CORPORATION (US) | 1976-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190030029-A1 | INGENOL ANALOGS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF | ERG28, PTH1R, CCR5 | ALDH1A1 1201/4885POLB 2037/4885TDP1 3949/4885 |
| US-10583140-B2 | Ingenol analogs, pharmaceutical compositions and methods of use thereof | ERG28, PTH1R, CCR5 | ALDH1A1 1201/4885POLB 2037/4885TDP1 3949/4885 |
| US-20250263395-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | CDK2, SKP2, CDK1 | ALDH1A1 3818/4885POLB 1173/4885TDP1 2330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.