Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 4/20 | 0.34 |
| ▸ | HTR7 | P34969 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.32 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | CCR3 | P51677 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.30 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21072473 | 0.79 | HTR7 (0.42) | HTR1AHTR7HTR2ASSTR5HRH1 | |
| SCHEMBL19852469 | 0.79 | PPARG (0.40) | PPARGPPARDHTR1ASMN1; SMN2 | |
| SCHEMBL19852465 | 0.76 | HTR7 (0.40) | HTR1AHTR7DRD2HTR2ASSTR5 | |
| SCHEMBL19852425 | 0.75 | HTR7 (0.42) | HTR1AHTR7HTR2AHRH1CCR3 | |
| SCHEMBL21071647 | 0.75 | FPR2 (0.38) | HTR1ACARM1PRMT6SMN1; SMN2 | |
| SCHEMBL19838628 | 0.70 | HTR2A (0.41) | HTR1AHTR7HTR2AHRH1CCR3 | |
| Hydrochloric Acid SCHEMBL19838581 | 0.70 | HTR2A (0.41) | HTR1AHTR7HTR2AHRH1CCR3 | |
| SCHEMBL19852330 | 0.70 | HTR7 (0.45) | HTR7HTR2AFFAR1SSTR5CARM1 | |
| SCHEMBL19852460 | 0.69 | KCNH2 (0.46) | HTR1ADRD2 | |
| SCHEMBL19852466 | 0.68 | CARM1 (0.47) | HTR1AHTR7DRD2HTR2ACARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026371-A1 | DUAL NAV1.2/5HT2A INHIBITORS FOR TREATING CNS DISORDERS | SUNOVION PHARMACEUTICALS INC. (US) | 2018-02-08 | — | — | WO | disclosed |