Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21071570 | 0.85 | SIGMAR1 (0.41) | HTR2AHTR2CHRH1TMEM97SIGMAR1 | |
| SCHEMBL19838621 | 0.85 | SIGMAR1 (0.41) | HTR2AHTR2CHRH1TMEM97SIGMAR1 | |
| SCHEMBL21071569 | 0.85 | SIGMAR1 (0.41) | HTR2AHTR2CHRH1TMEM97SIGMAR1 | |
| SCHEMBL19852495 | 0.85 | SIGMAR1 (0.41) | HTR2AHTR2CHRH1TMEM97SIGMAR1 | |
| SCHEMBL21071634 | 0.85 | SIGMAR1 (0.41) | HTR2AHTR2CHRH1TMEM97SIGMAR1 | |
| SCHEMBL21071451 | 0.85 | SIGMAR1 (0.41) | HTR2AHTR2CHRH1TMEM97SIGMAR1 | |
| SCHEMBL21071454 | 0.85 | SIGMAR1 (0.41) | HTR2AHTR2CHRH1TMEM97SIGMAR1 | |
| SCHEMBL19852237 | 0.75 | HTR2A (0.37) | HTR2AHTR2CHRH1TMEM97SIGMAR1 | |
| SCHEMBL19852493 | 0.71 | OPRL1 (0.39) | SIGMAR1OPRM1OPRL1 | |
| SCHEMBL19852490 | 0.71 | OPRL1 (0.39) | SIGMAR1OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026371-A1 | DUAL NAV1.2/5HT2A INHIBITORS FOR TREATING CNS DISORDERS | SUNOVION PHARMACEUTICALS INC. (US) | 2018-02-08 | — | — | WO | disclosed |