Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19852493 | 1.00 | OPRL1 (0.39) | OPRL1OPRM1KCNH2SIGMAR1HSD11B1 | |
| SCHEMBL21071570 | 0.83 | SIGMAR1 (0.41) | OPRL1OPRM1SIGMAR1HSD11B1HTR1A | |
| SCHEMBL19838621 | 0.83 | SIGMAR1 (0.41) | OPRL1OPRM1SIGMAR1HSD11B1HTR1A | |
| SCHEMBL21071634 | 0.83 | SIGMAR1 (0.41) | OPRL1OPRM1SIGMAR1HSD11B1HTR1A | |
| SCHEMBL21071569 | 0.83 | SIGMAR1 (0.41) | OPRL1OPRM1SIGMAR1HSD11B1HTR1A | |
| SCHEMBL21071454 | 0.83 | SIGMAR1 (0.41) | OPRL1OPRM1SIGMAR1HSD11B1HTR1A | |
| SCHEMBL19852495 | 0.83 | SIGMAR1 (0.41) | OPRL1OPRM1SIGMAR1HSD11B1HTR1A | |
| SCHEMBL21071451 | 0.83 | SIGMAR1 (0.41) | OPRL1OPRM1SIGMAR1HSD11B1HTR1A | |
| SCHEMBL21071954 | 0.81 | HTR7 (0.40) | OPRL1OPRM1SIGMAR1HSD11B1HTR1A | |
| SCHEMBL21071936 | 0.81 | HTR7 (0.40) | OPRL1OPRM1SIGMAR1HSD11B1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026371-A1 | DUAL NAV1.2/5HT2A INHIBITORS FOR TREATING CNS DISORDERS | SUNOVION PHARMACEUTICALS INC. (US) | 2018-02-08 | — | — | WO | disclosed |