Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | DRD3 | P35462 | 8/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.49 |
| ▸ | DRD2 | P14416 | 7/20 | 0.49 |
| ▸ | DRD4 | P21917 | 7/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.49 |
| ▸ | PER2 | O15055 | 1/20 | 0.47 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19852470 | 0.86 | PRMT5 (0.50) | DRD3DRD2DRD4PER2CRY2 | |
| SCHEMBL7421817 | 0.80 | POLB (0.59) | POLBDRD3CHRM2CHRM1DRD2 | |
| SCHEMBL41624 | 0.78 | MEN1 (0.40) | POLBCHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL4096279 | 0.78 | POLB (0.57) | POLBDRD3CHRM2CHRM1DRD2 | |
| SCHEMBL7251698 | 0.78 | POLB (0.57) | POLBDRD3CHRM2CHRM1DRD2 | |
| SCHEMBL4097259 | 0.78 | DRD3 (0.55) | POLBDRD3CHRM2CHRM1DRD2 | |
| SCHEMBL4095573 | 0.78 | DRD3 (0.55) | POLBDRD3CHRM2CHRM1DRD2 | |
| SCHEMBL4096281 | 0.78 | POLB (0.57) | POLBDRD3CHRM2CHRM1DRD2 | |
| SCHEMBL4097262 | 0.78 | DRD3 (0.55) | POLBDRD3CHRM2CHRM1DRD2 | |
| SCHEMBL4095572 | 0.78 | DRD3 (0.55) | POLBDRD3CHRM2CHRM1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11186564-B2 | Dual NAV1.2/5HT2a inhibitors for treating CNS disorders | SUNOVION PHARMACEUTICALS INC. (US) | 2021-11-30 | — | — | US | disclosed |
| US-20190194163-A1 | DUAL NAV1.2/5HT2a INHIBITORS FOR TREATING CNS DISORDERS | SUNOVION PHARMACEUTICALS INC. (US) | 2019-06-27 | — | — | US | disclosed |
| WO-2018026371-A1 | DUAL NAV1.2/5HT2A INHIBITORS FOR TREATING CNS DISORDERS | SUNOVION PHARMACEUTICALS INC. (US) | 2018-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194163-A1 | DUAL NAV1.2/5HT2a INHIBITORS FOR TREATING CNS DISORDERS | SCN2A, HTR2A, HTR2C | POLB 3235/4885DRD3 290/4885CHRM2 325/4885 |
| US-11186564-B2 | Dual NAV1.2/5HT2a inhibitors for treating CNS disorders | SCN2A, HTR2A, HTR2C | POLB 3235/4885DRD3 290/4885CHRM2 325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.