SCHEMBL41624

SCHEMBL41624

COC(CN1C(=O)CCC1=O)OC

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.40
TSHR P16473 1/20 0.40
KMT2A Q03164 1/20 0.40
GAA P10253 2/20 0.37
POLB P06746 2/20 0.36
HPGD P15428 3/20 0.35
HTT P42858 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ALDH1A1 P00352 3/20 0.34
PIK3CD O00329 1/20 0.32
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10669708 0.78 PKM (0.42) MEN1TSHRKMT2AGAAPOLB
SCHEMBL19852526 0.78 POLB (0.55) TSHRPOLBCHRM2CHRM4CHRM5
SCHEMBL13985879 0.75 HPGD (0.38) MEN1TSHRKMT2AGAAPOLB
SCHEMBL11476339 0.74 PIK3CD (0.47) TSHRGAAHPGDSMN1; SMN2ALDH1A1
SCHEMBL1682032 0.73 PIK3CD (0.50) MEN1TSHRKMT2AGAAPOLB
SCHEMBL8161159 0.73 MGLL (0.46) HPGDHTTSMN1; SMN2ALDH1A1
SCHEMBL5663770 0.73 ALDH1A1 (0.38) ALDH1A1
SCHEMBL14606115 0.72 PIK3CD (0.41) MEN1TSHRKMT2AGAAPOLB
SCHEMBL7466805 0.71 GSK3A (0.50) MEN1KMT2AGAAPOLBHTT
SCHEMBL22508467 0.71 PIK3CD (0.63) TSHRGAAHPGDALDH1A1PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012002913-A1 PROCESS OF FORMING A CYCLIC IMIDE NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2012-01-05 WO disclosed