Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19768828 | 0.91 | HPGD (0.50) | HPGDRECQLEPHX1ALDH1A1MAPT | |
| SCHEMBL18015117 | 0.90 | HPGD (0.46) | USP30HPGDPIK3CDPRMT5WDR77 | |
| SCHEMBL18015122 | 0.90 | HPGD (0.46) | USP30HPGDPIK3CDPRMT5WDR77 | |
| SCHEMBL18015131 | 0.90 | HPGD (0.46) | USP30HPGDPIK3CDPRMT5WDR77 | |
| SCHEMBL3332529 | 0.88 | HPGD (0.47) | USP30HPGDPIK3CDPRMT5WDR77 | |
| SCHEMBL15802795 | 0.88 | HPGD (0.47) | USP30HPGDPIK3CDPRMT5WDR77 | |
| SCHEMBL3332523 | 0.88 | HPGD (0.47) | USP30HPGDPIK3CDPRMT5WDR77 | |
| SCHEMBL19768827 | 0.88 | NR1H2 (0.46) | USP30HPGDPRMT5WDR77RECQL | |
| SCHEMBL19674641 | 0.87 | PIK3CD (0.47) | USP30HPGDPIK3CDPRMT5WDR77 | |
| SCHEMBL18839712 | 0.84 | USP30 (0.46) | USP30HPGDPIK3CDPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026371-A1 | DUAL NAV1.2/5HT2A INHIBITORS FOR TREATING CNS DISORDERS | SUNOVION PHARMACEUTICALS INC. (US) | 2018-02-08 | — | — | WO | disclosed |