Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19850917 | 0.78 | HSPA1A (0.45) | KDM4EPOLBRECQLTDP1CA1 | |
| SCHEMBL19843576 | 0.77 | PDE6D (0.34) | NPC1RAB9AKDM4EESR1POLB | |
| SCHEMBL19850922 | 0.76 | NPC1 (0.50) | NPC1RAB9AKDM4EESR1POLB | |
| SCHEMBL23476463 | 0.74 | KDM4E (0.37) | NPC1RAB9AKDM4EESR1POLB | |
| SCHEMBL19842574 | 0.73 | ALDH1A1 (0.39) | KDM4EPOLBRECQLTDP1ATM | |
| SCHEMBL19843085 | 0.73 | PRKDC (0.35) | ATM | |
| SCHEMBL19848955 | 0.73 | CA1 (0.38) | KDM4EPOLBCA1CA2ATM | |
| SCHEMBL19842386 | 0.72 | PDE6D (0.46) | KDM4EPOLBAPEX1RECQLTDP1 | |
| SCHEMBL19842498 | 0.72 | NR1H2 (0.44) | KDM4EPOLBHSD17B10CA1CA2 | |
| SCHEMBL19850918 | 0.72 | HSPA1A (0.43) | KDM4EPOLBRECQLTDP1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018024723-A1 | PHTHALIMIDE AND CARBAZOLE OR ANALOGS THEREOF CONTAINING COMPOUNDS FOR USE IN ORGANIC OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2018-02-08 | — | — | WO | disclosed |