⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258254 | 1.00 | — | — | |
| SCHEMBL2438529 | 0.83 | ALDH1A1 (0.43) | — | |
| SCHEMBL6948738 | 0.82 | TSHR (0.40) | — | |
| SCHEMBL7248705 | 0.81 | THRB (0.36) | — | |
| SCHEMBL16074671 | 0.81 | THRB (0.36) | — | |
| SCHEMBL8532460 | 0.81 | — | — | |
| SCHEMBL21247892 | 0.81 | TDP1 (0.38) | — | |
| SCHEMBL11197794 | 0.80 | — | — | |
| SCHEMBL5907081 | 0.79 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL560827 | 0.78 | THRB (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190359557-A1 | PICOLINAMIDES WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2019-11-28 | — | — | US | disclosed |
| US-10252989-B2 | Picolinamides with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2019-04-09 | — | — | US | disclosed |
| US-10173971-B2 | Picolinamides with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2019-01-08 | — | — | US | disclosed |
| US-20180037541-A1 | PICOLINAMIDES WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC | 2018-02-08 | — | — | US | disclosed |