Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MITF | O75030 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21581226 | 0.90 | TDP1 (0.39) | RAB9AMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL30129515 | 0.89 | TAS1R3 (0.37) | RAB9ANPC1HTTTAS1R3TAS1R1 | |
| SCHEMBL25042352 | 0.89 | TAS1R3 (0.37) | RAB9ANPC1HTTTAS1R3TAS1R1 | |
| SCHEMBL23706479 | 0.89 | TAS1R3 (0.37) | RAB9ANPC1HTTTAS1R3TAS1R1 | |
| SCHEMBL23706478 | 0.89 | TAS1R3 (0.37) | RAB9ANPC1HTTTAS1R3TAS1R1 | |
| SCHEMBL20352980 | 0.88 | TDP1 (0.38) | RAB9ANPC1HTTMEN1KMT2A | |
| SCHEMBL17904861 | 0.88 | NPC1 (0.32) | RAB9ANPC1HTTTAS1R3TAS1R1 | |
| SCHEMBL17901469 | 0.86 | TDP1 (0.40) | RAB9AMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL17904850 | 0.86 | TSHR (0.35) | RAB9ANPC1HTTTAS1R3TAS1R1 | |
| SCHEMBL17904860 | 0.86 | CNR2 (0.32) | RAB9ANPC1HTTTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190359557-A1 | PICOLINAMIDES WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2019-11-28 | — | — | US | disclosed |
| US-20180037541-A1 | PICOLINAMIDES WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC | 2018-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180037541-A1 | PICOLINAMIDES WITH FUNGICIDAL ACTIVITY | CYP51A1, CYP1A2, FKBP14 | RAB9A 4314/4885NPC1 1699/4885HTT 3724/4885 |
| US-20190359557-A1 | PICOLINAMIDES WITH FUNGICIDAL ACTIVITY | CYP51A1, CYP1A2, FKBP14 | RAB9A 4314/4885NPC1 1699/4885HTT 3724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.