Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | GALR2 | O43603 | 2/20 | 0.34 |
| ▸ | GALR1 | P47211 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19846880 | 0.83 | PTGDR2 (0.48) | ATMPTGDR2 | |
| SCHEMBL16562301 | 0.79 | MEN1 (0.46) | TRPV1SLC6A4TMEM97SIGMAR1KIF11 | |
| SCHEMBL30609128 | 0.78 | FFAR4 (0.40) | KIF11GPR3EPHX2HRH4EPHX1 | |
| SCHEMBL20526515 | 0.75 | HRH4 (0.43) | TRPV1SLC6A4KIF11GPR3EPHX2 | |
| SCHEMBL26794589 | 0.74 | TRPV1 (0.42) | TRPV1TAS1R3TAS1R1TAS1R2KIF11 | |
| SCHEMBL16838799 | 0.72 | GRM7 (0.45) | PTGDR2 | |
| SCHEMBL13439935 | 0.72 | GPR3 (0.44) | TRPV1KIF11GPR3HRH4SLC6A3 | |
| SCHEMBL14155817 | 0.72 | PDE2A (0.45) | TRPV1KIF11GPR3SLC6A3 | |
| SCHEMBL25589644 | 0.72 | GPR3 (0.43) | TRPV1KIF11GPR3SLC6A3 | |
| SCHEMBL21617078 | 0.71 | GPR3 (0.40) | TRPV1SLC6A4KIF11GPR3HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180037572-A1 | UREA DERIVATIVES AND USES THEREOF | KALA BIO, Inc. | 2018-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180037572-A1 | UREA DERIVATIVES AND USES THEREOF | UACA, RB1, FLT1 | TRPV1 2049/4885TAS1R3 651/4885TAS1R1 981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.