SCHEMBL1985352

SCHEMBL1985352

COc1ccc(C(=O)OCC(C)C)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.66
ADRB1 P08588 1/20 0.66
ADRB3 P13945 1/20 0.66
CA1 P00915 3/20 0.58
CA2 P00918 3/20 0.58
ESR2 Q92731 1/20 0.55
ALDH1A1 P00352 1/20 0.53
TSHR P16473 1/20 0.53
MAPT P10636 2/20 0.53
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
PLA2G1B P04054 1/20 0.52
ATG4B Q9Y4P1 1/20 0.52
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
ACHE P22303 1/20 0.49
GSK3B P49841 1/20 0.49
HDAC3 O15379 1/20 0.49
HDAC4 P56524 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL110051 0.89 ALDH1A1 (0.64) ADRB2ADRB1ADRB3CA1CA2
SCHEMBL13399586 0.87 ADRB2 (0.63) ADRB2ADRB1ADRB3CA1CA2
SCHEMBL27668352 0.87 ALDH1A1 (0.62) ADRB2ADRB1ADRB3CA1CA2
SCHEMBL27668055 0.87 ALDH1A1 (0.62) ADRB2ADRB1ADRB3CA1CA2
SCHEMBL27667934 0.87 ALDH1A1 (0.62) ADRB2ADRB1ADRB3CA1CA2
SCHEMBL27929357 0.86 KMT2A (0.60) ADRB2ADRB1ADRB3ALDH1A1TSHR
SCHEMBL5166149 0.85 TSHR (0.56) ADRB2ADRB1ADRB3CA1CA2
SCHEMBL1988771 0.85 MAPT (0.71) ADRB2ADRB1ADRB3CA1CA2
SCHEMBL12017972 0.84 ADRB2 (0.60) ADRB2ADRB1ADRB3CA1CA2
SCHEMBL5665246 0.84 ADRB2 (0.60) ADRB2ADRB1ADRB3CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2516479-B1 NEW INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS BASF CORP (US) 2016-04-20 EP claimed
CN-102762602-B New internal and external donor compounds for olefin polymerization catalysts BASF CORP 2014-08-13 CN claimed
EP-2516479-A2 NEW INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS BASF Corporation (US) 2012-10-31 EP claimed
CN-102762602-A New internal and external donor compounds for olefin polymerization catalysts BASF CORP 2012-10-31 CN claimed
US-8211819-B2 Internal and external donor compounds for olefin polymerization catalysts BASF CORPORATION (US) 2012-07-03 US claimed
WO-2011084691-A2 NEW INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS BASF CORPORATION (US) 2011-07-14 WO claimed
US-20110152481-A1 Internal and external donor compounds for olefin polymerization catalysts BASF CATALYSTS LLC (US) 2011-06-23 US claimed
CN-119708924-A Ink, ink preparation method and ink-jet printing method 广东聚华印刷显示技术有限公司 2025-03-28 CN disclosed
CN-113324736-B Optical detection method for refractive index matching liquid and glass 光华科学技术研究院(广东)有限公司 2024-11-19 CN disclosed
CN-113324736-B Optical detection method for refractive index matching liquid and glass 光华科学技术研究院(广东)有限公司 2024-11-19 CN disclosed
CN-113533253-B Refractive index matching liquid and application thereof in optical detection of glass 光华科学技术研究院(广东)有限公司 2024-07-12 CN disclosed
US-11377580-B2 Methods for in situ formation of high glass transition temperature polymers SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2022-07-05 US disclosed
CN-104829756-B A kind of solid catalyst component for olefine polymerization and its preparation method and application 中国科学院化学研究所 2018-05-15 CN disclosed
EP-2516479-A2 NEW INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS BASF Corporation (US) 2012-10-31 EP disclosed
CN-102762602-A New internal and external donor compounds for olefin polymerization catalysts BASF CORP 2012-10-31 CN disclosed
US-8211819-B2 Internal and external donor compounds for olefin polymerization catalysts BASF CORPORATION (US) 2012-07-03 US disclosed
WO-2011084691-A2 NEW INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS BASF CORPORATION (US) 2011-07-14 WO disclosed
US-20110152481-A1 Internal and external donor compounds for olefin polymerization catalysts BASF CATALYSTS LLC (US) 2011-06-23 US disclosed
CN-101534862-A External preparation for skin ROHTO PHARMA (JP) 2009-09-16 CN disclosed
EP-0050497-A1 Catalyst components for polymerization of alpha-olefins and processes for their preparation and use TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1982-04-28 EP disclosed