SCHEMBL19853801

SCHEMBL19853801

C=CC(=O)NCCCc1ccc2cc(-c3ccc(C4CCC(CCCCC)CC4)cc3F)ccc2c1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 1/20 0.38
▸ RARB P10826 1/20 0.36
▸ FAAH O00519 1/20 0.36
▸ PTGS2 P35354 1/20 0.36
▸ BTK Q06187 2/20 0.35
▸ ZDHHC20 Q5W0Z9 1/20 0.34
▸ ZDHHC2 Q9UIJ5 1/20 0.34
▸ DGAT1 O75907 1/20 0.34
▸ THRB P10828 2/20 0.33
▸ THRA P10827 1/20 0.33
▸ FASN P49327 1/20 0.33
▸ TGM2 P21980 1/20 0.33
▸ SPHK1 Q9NYA1 1/20 0.33
▸ FFAR4 Q5NUL3 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19855147 0.93 RARB (0.43) GAARARBBTKZDHHC20ZDHHC2
SCHEMBL19855149 0.91 RARB (0.41) GAARARBFAAHPTGS2ZDHHC20
SCHEMBL19854016 0.90 RARB (0.41) GAARARBFAAHPTGS2BTK
SCHEMBL19855116 0.88 DGAT1 (0.38) GAARARBFAAHPTGS2BTK
SCHEMBL20370573 0.88 RARB (0.42) GAARARBZDHHC20ZDHHC2DGAT1
SCHEMBL20370578 0.88 RARB (0.42) GAARARBZDHHC20ZDHHC2DGAT1
SCHEMBL19854470 0.86 BTK (0.38) RARBBTKTHRBFASNSPHK1
SCHEMBL19853804 0.85 RARB (0.45) GAARARBFAAHPTGS2ZDHHC20
SCHEMBL20370480 0.84 THRA (0.38) BTKDGAT1THRBTHRAFASN
SCHEMBL19855838 0.84 RARB (0.41) RARBBTKZDHHC20ZDHHC2DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 — — US disclosed
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed
WO-2018025974-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND DISPLAY DEVICE JNC株式会社 2018-02-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE SP1, MBD2, PAXBP1 GAA 4879/4885RARB 1437/4885FAAH 3511/4885
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device SP1, MBD2, PAXBP1 GAA 4879/4885RARB 1437/4885FAAH 3511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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