SCHEMBL19854009

SCHEMBL19854009

C=CC(=O)NCCOc1ccc(-c2ccc(C3CCC(C4CCC(CCCCC)CC4)CC3)c(F)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ RARB P10826 2/20 0.41
▸ RARA P10276 1/20 0.41
▸ ITGB3 P05106 2/20 0.35
▸ ITGA2B P08514 2/20 0.35
▸ NR4A2 P43354 1/20 0.34
▸ DHODH Q02127 1/20 0.34
▸ EGFR P00533 1/20 0.34
▸ OPRL1 P41146 4/20 0.34
▸ CNR2 P34972 1/20 0.34
▸ ITK Q08881 1/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ MTNR1A P48039 1/20 0.34
▸ MTNR1B P49286 1/20 0.34
▸ DGAT1 O75907 1/20 0.34
▸ SCN9A Q15858 1/20 0.33
▸ BTK Q06187 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20370561 0.87 RAB9A (0.44) RARBITGB3ITGA2BITKRAB9A
SCHEMBL19855821 0.86 RARB (0.40) RARBRARAITGB3ITGA2BCNR2
SCHEMBL20370541 0.85 CNR2 (0.38) ITGB3ITGA2BEGFRCNR2ITK
SCHEMBL19855104 0.85 RARB (0.41) RARBRARAITGB3ITGA2BNR4A2
SCHEMBL19855825 0.85 OPRL1 (0.39) OPRL1DGAT1
SCHEMBL20370465 0.84 RAB9A (0.46) RARBITGB3ITGA2BITKRAB9A
SCHEMBL20370456 0.84 RAB9A (0.46) ITGB3ITGA2BITKRAB9A
SCHEMBL19855141 0.82 ITK (0.41) RARBRARAEGFRITKDGAT1
SCHEMBL19854169 0.82 RARA (0.40) RARBRARAITGB3ITGA2BCNR2
SCHEMBL19855283 0.82 BTK (0.38) OPRL1ITKBTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 — — US disclosed
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed
WO-2018025974-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND DISPLAY DEVICE JNC株式会社 2018-02-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE SP1, MBD2, PAXBP1 RARB 1437/4885RARA 1599/4885ITGB3 3928/4885
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device SP1, MBD2, PAXBP1 RARB 1437/4885RARA 1599/4885ITGB3 3928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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