SCHEMBL19854529

SCHEMBL19854529

C=CC(=O)Nc1ccc(CCCCCCC)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
THRB P10828 8/20 1.00
THRA P10827 7/20 1.00
MEN1 O00255 1/20 0.61
KMT2A Q03164 1/20 0.61
SPHK1 Q9NYA1 8/20 0.57
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA9 Q16790 1/20 0.56
S1PR1 P21453 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2728759 1.00 THRB (1.00) THRBTHRAMEN1KMT2ASPHK1
SCHEMBL2729131 1.00 THRB (1.00) THRBTHRAMEN1KMT2ASPHK1
SCHEMBL9864844 1.00 THRB (1.00) THRBTHRAMEN1KMT2ASPHK1
SCHEMBL2727638 1.00 THRB (1.00) THRBTHRAMEN1KMT2ASPHK1
SCHEMBL29175026 0.98 THRB (0.97) THRBTHRAMEN1KMT2ASPHK1
SCHEMBL19855850 0.94 THRB (0.89) THRBTHRAMEN1KMT2ASPHK1
SCHEMBL6677167 0.94 THRA (0.88) THRBTHRAMEN1KMT2ACA12
SCHEMBL15756377 0.92 THRA (0.85) THRBTHRAMEN1KMT2ASPHK1
SCHEMBL20469633 0.90 THRB (0.82) THRBTHRAMEN1KMT2ASPHK1
SCHEMBL20370424 0.89 THRB (0.80) THRBTHRAMEN1KMT2ASPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 US disclosed
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 US disclosed
WO-2018025974-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND DISPLAY DEVICE JNC株式会社 2018-02-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE SP1, MBD2, PAXBP1 THRB 3939/4885THRA 3929/4885MEN1 73/4885
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device SP1, MBD2, PAXBP1 THRB 3939/4885THRA 3929/4885MEN1 73/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.