Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.39 |
| ▸ | TUBB | P07437 | 2/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5858046 | 0.93 | EGFR (0.51) | EGFRCYP1A2HDAC3TDP1HDAC8 | |
| SCHEMBL5858044 | 0.93 | EGFR (0.51) | EGFRCYP1A2HDAC3TDP1HDAC8 | |
| SCHEMBL8722883 | 0.93 | EGFR (0.51) | EGFRCYP1A2HDAC3TDP1HDAC8 | |
| SCHEMBL8722881 | 0.93 | EGFR (0.51) | EGFRCYP1A2HDAC3TDP1HDAC8 | |
| SCHEMBL579053 | 0.85 | EGFR (0.49) | EGFRCYP1A2HDAC3TDP1HDAC8 | |
| SCHEMBL6526872 | 0.78 | HDAC3 (0.43) | EGFRCYP1A2HDAC3TDP1HDAC8 | |
| SCHEMBL7761258 | 0.77 | MEN1 (0.42) | EGFRCYP1A2HDAC3TDP1HDAC8 | |
| SCHEMBL21716147 | 0.77 | EGFR (0.47) | EGFRCYP1A2HDAC3TDP1HDAC8 | |
| SCHEMBL11415941 | 0.77 | EGFR (0.50) | EGFRHDAC3TDP1HDAC8HDAC6 | |
| SCHEMBL29849770 | 0.77 | HDAC3 (0.45) | CYP1A2HDAC3TDP1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558427-B1 | ABRASIVE ARTICLES AND METHOD OF MAKING AND USING THE ARTICLES | 3M INNOVATIVE PROPERTIES CO (US) | 2011-06-29 | — | — | EP | disclosed |
| US-6951577-B2 | Abrasive articles and method of making and using the articles | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-10-04 | — | — | US | disclosed |
| EP-1558427-A1 | ABRASIVE ARTICLES AND METHOD OF MAKING AND USING THE ARTICLES | 3M Innovative Properties Company (US) | 2005-08-03 | — | — | EP | disclosed |
| US-20040144037-A1 | Abrasive articles and method of making and using the articles | 3M INNOVATIVE PROPERTIES COMPANY | 2004-07-29 | — | — | US | disclosed |
| WO-2004043650-A1 | ABRASIVE ARTICLES AND METHOD OF MAKING AND USING THE ARTICLES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2004-05-27 | — | — | WO | disclosed |