SCHEMBL579053

SCHEMBL579053

CCCCCCCCCCCCCC(C=Cc1ccccc1)C(C)=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.49
HDAC3 O15379 6/20 0.43
TDP1 Q9NUW8 2/20 0.42
TUBB4A P04350 2/20 0.41
TUBB P07437 2/20 0.41
TUBA3C P0DPH7 2/20 0.41
TUBA1B P68363 2/20 0.41
TUBA4A P68366 2/20 0.41
TUBB4B P68371 2/20 0.41
TUBB3 Q13509 2/20 0.41
TUBB2A Q13885 2/20 0.41
TUBB8 Q3ZCM7 2/20 0.41
TUBA3E Q6PEY2 2/20 0.41
TUBA1A Q71U36 2/20 0.41
TUBA1C Q9BQE3 2/20 0.41
TUBB6 Q9BUF5 2/20 0.41
TUBB2B Q9BVA1 2/20 0.41
TUBB1 Q9H4B7 2/20 0.41
HDAC8 Q9BY41 7/20 0.41
HDAC6 Q9UBN7 5/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8722883 0.91 EGFR (0.51) EGFRHDAC3TDP1TUBB4ATUBB
SCHEMBL8722881 0.91 EGFR (0.51) EGFRHDAC3TDP1TUBB4ATUBB
SCHEMBL5858046 0.91 EGFR (0.51) EGFRHDAC3TDP1TUBB4ATUBB
SCHEMBL5858044 0.91 EGFR (0.51) EGFRHDAC3TDP1TUBB4ATUBB
SCHEMBL5175602 0.88 GLA (0.46) EGFRHDAC3TDP1HDAC8HDAC6
Acrylic Acid SCHEMBL1985471 0.85 EGFR (0.46) EGFRHDAC3TDP1TUBB4ATUBB
Acetic Acid SCHEMBL28444976 0.81 EGFR (0.48) EGFRHDAC3TDP1TUBB4ATUBB
SCHEMBL27642615 0.78 EGFR (0.47) EGFRTDP1TUBB4ATUBBTUBA3C
SCHEMBL6526872 0.78 HDAC3 (0.43) EGFRHDAC3TDP1HDAC8HDAC6
SCHEMBL20873608 0.78 EGFR (0.45) EGFRHDAC3TDP1TUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3043906-A1 USE OF CERTAIN ORGANIC MATERIALS, CONTAINING ALKALI OR ALKALINE-EARTH METALS, FOR IMPLEMENTING ORGANIC CHEMICAL REACTIONS Centre National De La Recherche Scientifique (FR) 2016-07-20 EP disclosed
EP-1979435-B8 REVERSIBLE THERMOCHROMIC COMPOSITIONS BASF SE (DE) 2012-02-15 EP disclosed
EP-1979435-B1 REVERSIBLE THERMOCHROMIC COMPOSITIONS BASF SE (DE) 2011-05-25 EP disclosed
WO-2007085636-A1 REVERSIBLE THERMOCHROMIC COMPOSITIONS CIBA HOLDING INC. (CH) 2007-08-02 WO disclosed