SCHEMBL6526872

SCHEMBL6526872

C=C(C(=O)O)C(C=Cc1ccccc1)CCCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 3/20 0.43
HDAC4 P56524 2/20 0.43
HDAC1 Q13547 2/20 0.43
HDAC7 Q8WUI4 2/20 0.43
HDAC2 Q92769 2/20 0.43
HDAC10 Q969S8 2/20 0.43
HDAC11 Q96DB2 2/20 0.43
HDAC8 Q9BY41 2/20 0.43
HDAC6 Q9UBN7 2/20 0.43
HDAC9 Q9UKV0 2/20 0.43
HDAC5 Q9UQL6 2/20 0.43
EGFR P00533 1/20 0.42
LMNA P02545 2/20 0.41
TSHR P16473 1/20 0.41
CYP1A2 P05177 1/20 0.40
TDP1 Q9NUW8 3/20 0.38
NPC1 O15118 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CNR2 P34972 2/20 0.38
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11198475 0.89 HDAC3 (0.39) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL4879288 0.86 MEN1 (0.45) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL8352283 0.85 HDAC3 (0.40) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL4854245 0.82 BCHE (0.42) LMNACYP1A2NPC1L3MBTL1MEN1
SCHEMBL8722881 0.81 EGFR (0.51) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL8722883 0.81 EGFR (0.51) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL5858044 0.81 EGFR (0.51) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL5858046 0.81 EGFR (0.51) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL579053 0.78 EGFR (0.49) HDAC3HDAC4HDAC1HDAC7HDAC2
Acrylic Acid SCHEMBL1985471 0.78 EGFR (0.46) HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2822764-B1 METHOD AND DEVICE FOR THE SECURE PROTECTION OF OFFICIAL DOCUMENTS BY MEANS OF A TRANSPARENT FILM HAVING A SINGLE CONTINUOUS THERMOPLASTIC LAYER FASVER (FR) 2016-05-25 EP claimed
EP-0136181-B1 DEVELOPER COMPOSITION CONTAINING SUPERPARAMAGNETIC POLYMERS XEROX CORPORATION (US) 1988-01-07 EP claimed
US-9938225-B2 Biomass-derived methyl methacrylate and corresponding manufacturing method, uses and polymers ARKEMA FRANCE (FR) 2018-04-10 US disclosed
US-20140154758-A1 BIOMASS DERIVED METHYL METHACRYLATE AND CORRESPONDING MANUFACURING METHOD, USES AND POLYMERS TRINSEO EUROPE GMBH (CH) 2014-06-05 US disclosed
JP-2005206471-A CURABLE COMPOSITION FOR FLEXIBLE RELINING MATERIAL TOKUYAMA CORP 2005-08-04 JP disclosed
US-5882841-A ULTRAHIGH CONTRAST, STORAGE STABILITY, UNIFORMITY, POLYMER PARTICLES CONTAINING A HYDRAZINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1999-03-16 US disclosed
EP-0317983-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1994-06-01 EP disclosed
US-5100771-A SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL WITH WATER INSOLUBLE ORGANIC SOLVENT SOLUBLE POLYMER FUJI PHOTO FILM CO., LTD. (JP) 1992-03-31 US disclosed
US-5047314-A Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-09-10 US disclosed
EP-0317983-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-05-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140154758-A1 BIOMASS DERIVED METHYL METHACRYLATE AND CORRESPONDING MANUFACURING METHOD, USES AND POLYMERS PRMT6, MCM6, DNMT3A HDAC3 3546/4885HDAC4 4720/4885HDAC1 3858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.