Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24634181 | 0.92 | GRIN2B (0.41) | GRIN2BGRIN2COPRK1 | |
| SCHEMBL19853718 | 0.92 | GRIN2B (0.41) | GRIN2BGRIN2COPRK1 | |
| SCHEMBL19853728 | 0.79 | GRIN2B (0.42) | GRIN2BGRIN2C | |
| SCHEMBL19854301 | 0.79 | OPRK1 (0.30) | OPRK1 | |
| SCHEMBL19853735 | 0.78 | GRIN2B (0.41) | GRIN2BGRIN2C | |
| SCHEMBL19839385 | 0.77 | GRIN2B (0.46) | GRIN2BGRIN2C | |
| SCHEMBL19854372 | 0.77 | GRIN2B (0.46) | GRIN2BGRIN2C | |
| SCHEMBL19853754 | 0.77 | GRIN2B (0.46) | GRIN2BGRIN2C | |
| SCHEMBL19839370 | 0.77 | GRIN2B (0.46) | GRIN2BGRIN2C | |
| SCHEMBL19839367 | 0.77 | GRIN2B (0.46) | GRIN2BGRIN2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026763-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | APTINYX INC. (US) | 2018-02-08 | — | — | WO | disclosed |