SCHEMBL19855458

SCHEMBL19855458

C=C(CO)C(=O)OCCCC(CCCOC(=O)C(=C)CO)c1ccc(C2CCC(C3CCC(C4CCC(CCCCC)CC4)CC3)CC2)c(F)c1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ GPR139 Q6DWJ6 2/20 0.33
▸ OPRL1 P41146 5/20 0.31
▸ PDE2A O00408 5/20 0.31
▸ ACACB O00763 1/20 0.31
▸ FFAR1 O14842 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19855683 0.97 TSHR (0.33) GPR139OPRL1ACACB
SCHEMBL20882701 0.91 PDE2A (0.33) GPR139OPRL1PDE2A
SCHEMBL19856353 0.90 TSHR (0.34) GPR139OPRL1PDE2AACACB
SCHEMBL19721885 0.86 CYP2C9 (0.33) OPRL1
SCHEMBL19722115 0.86 CYP2C9 (0.33) OPRL1
SCHEMBL19722571 0.86 CYP2C9 (0.33) OPRL1
SCHEMBL19855408 0.86 CYP2C9 (0.39) ACACB
SCHEMBL20882743 0.86 GPR139 (0.31) GPR139ACACB
SCHEMBL21398492 0.85 GPR139 (0.32) GPR139PDE2A
SCHEMBL19722559 0.85 OPRL1 (0.34) OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 — — US disclosed
US-20190292463-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORPORATION (JP) 2019-09-26 — — US disclosed
EP-3466918-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2019-04-10 — — EP disclosed
WO-2018025974-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND DISPLAY DEVICE JNC株式会社 2018-02-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190292463-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT SP1, PYM1, MPEG1 GPR139 734/4885OPRL1 2531/4885PDE2A 4589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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