Sugi Predict

Sugi Predict / Targets / MPEG1

MPEG1

Macrophage-expressed gene 1 protein · Q2M385 · MPEG1 on Sugi Atlas →

1,938 patent compounds predicted against MPEG1, 905 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
Embelin Embelin (SCHEMBL148744) 1.00 11/20
Rapanone Rapanone (SCHEMBL2311835) 1.00 11/20
SCHEMBL12757276 SCHEMBL12757276 1.00 11/20
SCHEMBL6410428 SCHEMBL6410428 0.97 11/20
Embelin Embelin (SCHEMBL4653231) 0.88 11/20
SCHEMBL11148794 SCHEMBL11148794 0.68 11/20
SCHEMBL1020312 SCHEMBL1020312 0.65 11/20
SCHEMBL7365320 SCHEMBL7365320 0.65 11/20
SCHEMBL16466025 SCHEMBL16466025 0.64 11/20
SCHEMBL6206063 SCHEMBL6206063 0.63 11/20
SCHEMBL5554116 SCHEMBL5554116 0.62 11/20
SCHEMBL14507682 SCHEMBL14507682 0.62 11/20
SCHEMBL5554107 SCHEMBL5554107 0.58 11/20
SCHEMBL16465675 SCHEMBL16465675 0.56 11/20
SCHEMBL3273093 SCHEMBL3273093 0.55 11/20
SCHEMBL9444208 SCHEMBL9444208 0.55 11/20
SCHEMBL9857129 SCHEMBL9857129 0.55 11/20
SCHEMBL10337077 SCHEMBL10337077 0.55 11/20
SCHEMBL16465465 SCHEMBL16465465 0.54 11/20
SCHEMBL932791 SCHEMBL932791 0.51 11/20

Clinical trials — most relevant to MPEG1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
IRon Nanoparticle Enhanced MRI in the Assessment of Myocardial infarctioN PHASE2COMPLETED
Peptide Vaccine Focusing on Prevention of the Recurrence for Bladder Cancer PHASE2UNKNOWN
Novel Peptide Vaccination for Patients With Advanced Bladder Cancer PHASE1COMPLETED
Study on the Safety and Tolerability of PD-1 Knockout Tumor-infiltrating T Cells (TILs) in the Treatment of Advanced Colorectal Cancer PHASE1RECRUITING
Correlation Between Serum Markers of Unstable Plaque and Virtual Histology of Unstable Plaque Visualized by IVUS nanCOMPLETED
Hypomagnesemia and Its Association With Calcineurin Inhibitors Use in Renal Transplant Recipients nanCOMPLETED
Can Gdf-15 Level Predict Progression to Multiple Organ Failure in Patients With Septic Shock nanENROLLING_BY_INVITATION
Familial Myeloproliferative Disorders nanCOMPLETED
Expression Pattern and Possible Clinical Significance of CD81 In Myeloid Leukemia nanNOT_YET_RECRUITING
Celiac Disease Genomic Environmental Microbiome and Metabolomic Study nanRECRUITING
Chronic Obstructive Pulmonary Disease Gene Localization nanCOMPLETED
Genetic Basis of Mitral Valve Prolapse nanUNKNOWN
Melanocortin Gene Expression in Lymphocytes of Polymyalgia Patients nanCOMPLETED
PROOF: Pancreatitis-associated Risk Of Organ Failure nanCOMPLETED
Role of Genetics in Idiopathic Pulmonary Fibrosis (IPF) nanUNKNOWN
Gene-expression Profiles in CNS-metastatic Non-small Cell Lung Cancer nanUNKNOWN
Pathogenetic Basis of Aortopathy and Aortic Valve Disease nanACTIVE_NOT_RECRUITING
Identification of Genes and Pathogenesis Involved in Familial Thoracic Aortic Aneurysm nanCOMPLETED
Effects of Donor and Recipient Genetic Expression on Heart, Lung, Liver, or Kidney Transplant Survival nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Biomarkers and SNP-polymorphisms in Post-infarction Cardiac Remodeling nanCOMPLETED
Gene Expression, Metabolomic, Microbiome, and Calcium Metabolism in Response to Varied Vitamin D Dosages nanCOMPLETED
Cell Cycle Regulatory Gene Study in Patients With Myeloproliferative Disorders nanWITHDRAWN
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
Monocyte Chemoattractant Protein-1 in Psoriatic Arthritis Patients nanUNKNOWN
Linkage Study in Familial Pulmonary Fibrosis nanCOMPLETED
Lipidomics Screening of Anti-inflammatory Drugs and Drug Candidates in Vitro - Part A nanACTIVE_NOT_RECRUITING
Study of Mycobacterial Infections nanRECRUITING
The Role of Quantitative CT and Radiomic Biomarkers for Precision Medicine in Pulmonary Fibrosis nanRECRUITING
Prognostic Value of Protein IMP3 Expression in Cervical Cancer nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a MPEG1 binder may also engage these)

ProteinNameSimilarity
Q2KJC3 — 1.000 Q2KJC3 →
A1L314 — 0.999 A1L314 →
Q5RBP9 — 0.996 Q5RBP9 →
Q9WV57 — 0.996 Q9WV57 →
P35763 — 0.979 P35763 →
P10820 — 0.978 P10820 →
Q3MHN2 — 0.976 Q3MHN2 →
P2RX5 P2X purinoceptor 5 0.976 landscape →
Q66K08 — 0.976 Q66K08 →
Q9DBX3 — 0.976 Q9DBX3 →
Q5RAD0 — 0.975 Q5RAD0 →
P55314 — 0.975 P55314 →
Q8BH35 — 0.974 Q8BH35 →
P07357 — 0.974 P07357 →
Q9R1Q9 — 0.973 Q9R1Q9 →
Q5E9U1 — 0.973 Q5E9U1 →
P98136 — 0.973 P98136 →
Q9NS93 — 0.973 Q9NS93 →
Q66S13 — 0.973 Q66S13 →
LAMP2 Lysosome-associated membrane glycoprotein 2 0.973 landscape →
Q9TUQ3 — 0.972 Q9TUQ3 →
P15658 — 0.972 P15658 →
P10643 — 0.972 P10643 →
P06683 — 0.972 P06683 →
Q8BG22 — 0.972 Q8BG22 →
Q6DDW2 — 0.972 Q6DDW2 →
Q29RQ1 — 0.972 Q29RQ1 →
A8WFR0 — 0.971 A8WFR0 →
Q64663 — 0.971 Q64663 →
O95477 — 0.971 O95477 →