SCHEMBL19856026

SCHEMBL19856026

C=CC(=O)NCCc1ccc(-c2ccc(CCCCC)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRB P10828 7/20 0.62
THRA P10827 6/20 0.62
ZDHHC20 Q5W0Z9 1/20 0.55
ZDHHC2 Q9UIJ5 1/20 0.55
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
RARB P10826 7/20 0.54
ALDH1A1 P00352 2/20 0.52
RARA P10276 1/20 0.52
MAPT P10636 1/20 0.52
MTOR P42345 1/20 0.52
TGM2 P21980 1/20 0.49
CNR1 P21554 1/20 0.49
CNR2 P34972 1/20 0.49
SPHK1 Q9NYA1 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20370593 0.94 THRB (0.62) THRBTHRAZDHHC20ZDHHC2MEN1
SCHEMBL20370473 0.94 THRB (0.62) THRBTHRAZDHHC20ZDHHC2MEN1
SCHEMBL20370416 0.94 THRB (0.62) THRBTHRAZDHHC20ZDHHC2MEN1
SCHEMBL28482309 0.91 THRB (0.60) THRBTHRAZDHHC20ZDHHC2MEN1
SCHEMBL19856028 0.89 THRB (0.62) THRBTHRAZDHHC20ZDHHC2MEN1
SCHEMBL19854545 0.88 THRB (0.69) THRBTHRAZDHHC20ZDHHC2MEN1
SCHEMBL19854548 0.88 THRB (0.58) THRBTHRAZDHHC20ZDHHC2MEN1
SCHEMBL19856044 0.86 THRB (0.55) THRBTHRAZDHHC20ZDHHC2MEN1
SCHEMBL19854615 0.86 RARB (0.55) THRBTHRAZDHHC20ZDHHC2MEN1
SCHEMBL19854604 0.86 RARB (0.55) THRBTHRAZDHHC20ZDHHC2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 US disclosed
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 US disclosed
WO-2018025974-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND DISPLAY DEVICE JNC株式会社 2018-02-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE SP1, MBD2, PAXBP1 THRB 3939/4885THRA 3929/4885ZDHHC20 946/4885
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device SP1, MBD2, PAXBP1 THRB 3939/4885THRA 3929/4885ZDHHC20 946/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.